Polymer-Based Electrospun Nanofibers for Biomedical Applications

被引：164

作者：

Al-Enizi, Abdullah M. ^{[1
]}

Zagho, Moustafa M. ^{[2
]}

Elzatahry, Ahmed A. ^{[2
]}

机构：

[1] King Saud Univ, Dept Chem, POB 2455, Riyadh 11451, Saudi Arabia

[2] Qatar Univ, Coll Arts & Sci, Mat Sci & Technol Program, POB 2713, Doha, Qatar

来源：

NANOMATERIALS | 2018年 / 8卷 / 04期

关键词：

electrospinning; nanofibers; medical prostheses; wound dressing; drug release; tissue engineering; blood vessels; bone; CONTROLLED DRUG-RELEASE; COMPOSITE NANOFIBERS; ANTIBACTERIAL PROPERTIES; VASCULAR GRAFTS; TETRACYCLINE HYDROCHLORIDE; QUATERNIZED CHITOSAN; EXTRACELLULAR-MATRIX; DRESSING MATERIALS; TUBULAR SCAFFOLD; IN-VITRO;

D O I：

10.3390/nano8040259

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospinning has been considered a promising and novel procedure to fabricate polymer nanofibers due to its simplicity, cost effectiveness, and high production rate, making this technique highly relevant for both industry and academia. It is used to fabricate non-woven fibers with unique characteristics such as high permeability, stability, porosity, surface area to volume ratio, ease of functionalization, and excellent mechanical performance. Nanofibers can be synthesized and tailored to suit a wide range of applications including energy, biotechnology, healthcare, and environmental engineering. A comprehensive outlook on the recent developments, and the influence of electrospinning on biomedical uses such as wound dressing, drug release, and tissue engineering, has been presented. Concerns regarding the procedural restrictions and research contests are addressed, in addition to providing insights about the future of this fabrication technique in the biomedical field.

引用

页数：22

共 148 条

[1] Electrospun biphasic tubular scaffold with enhanced mechanical properties for vascular tissue engineering [J].

Abdal-hay, Abdalla ;

Bartnikowski, Michal ;

Hamlet, Stephen ;

Ivanovski, Saso .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 82 :10-18

[2]

Ahadian S., 2017, CLIN PRECLINICAL ASP

[3] Tetracycline hydrochloride-loaded electrospun nanofibers mats based on PVA and chitosan for wound dressing [J].

Alavarse, Alex Carvalho ;

de Oliveira Silva, Fernanda Waitman ;

Colque, Jandir Telleria ;

da Silva, Viviam Moura ;

Prieto, Tatiane ;

Venancio, Everaldo Carlos ;

Bonvent, Jean-Jacques .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 77 :271-281

[4] ELECTROSTATIC SPINNING OF ACRYLIC MICROFIBERS [J].

BAUMGARTEN, PK .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1971, 36 (01) :71-+

[5] Vascular Tissue Engineering: Effects of Integrating Collagen into a PCL Based Nanofiber Material [J].

Bertram, Ulf ;

Steiner, Dominik ;

Poppitz, Benjamin ;

Dippold, Dirk ;

Koehn, Katrin ;

Beier, Justus P. ;

Detsch, Rainer ;

Boccaccini, Aldo R. ;

Schubert, Dirk W. ;

Horch, Raymund E. ;

Arkudas, Andreas .

BIOMED RESEARCH INTERNATIONAL, 2017, 2017

[6] Electrospinning: A fascinating fiber fabrication technique [J].

Bhardwaj, Nandana ;

Kundu, Subhas C. .

BIOTECHNOLOGY ADVANCES, 2010, 28 (03) :325-347

[7] Effects of nonwoven mats of di-O-butyrylchitin and related polymers on the process of wound healing [J].

Blasinska, Anna ;

Drobnik, Jacek .

BIOMACROMOLECULES, 2008, 9 (03) :776-782

[8] Fabrication and Characterization of Electrospun PCL-MgO-Keratin-Based Composite Nanofibers for Biomedical Applications [J].

Boakye, Maame A. D. ;

Rijal, Nava P. ;

Adhikari, Udhab ;

Bhattarai, Narayan .

MATERIALS, 2015, 8 (07) :4080-4095

[9]

Bognitzki M, 2001, ADV MATER, V13, P70, DOI 10.1002/1521-4095(200101)13:1<70::AID-ADMA70>3.3.CO

[10]

2-8

← 1 2 3 4 5 6 7 8 9 10 →