Defining and treating moderate plaque psoriasis: a dermatologist survey

被引:20
作者
Knuckles, Melissa L. F. [1 ]
Levi, Eugenia [2 ]
Soung, Jennifer [3 ]
机构
[1] Dept Dermatol, Richmond, KY USA
[2] Celgene Corp, Summit, NJ USA
[3] Southern Calif Dermatol, Santa Ana, CA USA
关键词
Psoriasis; online survey; dermatologists; disease severity; treatment; SAFETY TRIAL; PHASE-III; EFFICACY; APREMILAST; MANAGEMENT; INHIBITOR; ARTHRITIS; GUIDELINES; BARRIERS; CARE;
D O I
10.1080/09546634.2018.1443200
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Purpose: Patients with moderate plaque psoriasis are often undertreated and may experience unsatisfactory clinical outcomes. Undertreatment may stem partly from a lack of consensus on the definition of moderate psoriasis and appropriate treatments for patients with moderate disease severity.Materials and Methods: An online survey was conducted during October 2015 to determine how US dermatologists in the clinical setting define and treat moderate psoriasis.Results: A total of 150 dermatologists responded to the survey (mean time in practice: 13.5years). On average, they saw 72 patients with psoriasis per month; 40% of these patients were considered to have moderate psoriasis. Most (95%) reported assessing disease severity based on the percentage of psoriasis-affected body surface area (BSA); 59% also considered location of the affected area. BSA cutoffs used to define moderate psoriasis varied widely (median low and high cutoffs: 5-10%; range: 1-70%). Similarly, wide variation in cutoff ranges was observed for the Psoriasis Area and Severity Index (PASI), Physician Global Assessment (PGA), and Dermatology Life Quality Index (DLQI). Primary therapy comprised biologics (47%), prescription topicals (28%), and oral systemics (18%).Conclusions: The current findings indicate lack of consensus surrounding the definition of moderate psoriasis among US dermatologists.
引用
收藏
页码:658 / 663
页数:6
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