Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer

被引：524
作者：
Miyaki, M
Konishi, M
Tanaka, K
KikuchiYanoshita, R
Muraoka, M
Yasuno, M
Igari, T
Koike, M
Chiba, M
Mori, T
机构：
[1] TOKYO METROPOLITAN KOMAGOME HOSP,DEPT PATHOL,BUNKYO KU,TOKYO 113,JAPAN
[2] TOKYO METROPOLITAN KOMAGOME HOSP,DEPT SURG,BUNKYO KU,TOKYO 113,JAPAN
[3] AKITA UNIV,DEPT INTERNAL MED 1,AKITA 010,JAPAN
来源：
NATURE GENETICS | 1997年 / 17卷 / 03期
关键词：
D O I：
10.1038/ng1197-271
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
引用
收藏
页码：271 / 272
页数：2
相关论文
共 15 条
  • [1] CLUES TO THE PATHOGENESIS OF FAMILIAL COLORECTAL-CANCER
    AALTONEN, LA
    PELTOMAKI, P
    LEACH, FS
    SISTONEN, P
    PYLKKANEN, L
    MECKLIN, JP
    JARVINEN, H
    POWELL, SM
    JEN, J
    HAMILTON, SR
    PETERSEN, GM
    KINZLER, KW
    VOGELSTEIN, B
    DELACHAPELLE, A
    [J]. SCIENCE, 1993, 260 (5109) : 812 - 816
  • [2] MUTATION IN THE DNA MISMATCH REPAIR GENE HOMOLOG HMLH1 IS ASSOCIATED WITH HEREDITARY NONPOLYPOSIS COLON-CANCER
    BRONNER, CE
    BAKER, SM
    MORRISON, PT
    WARREN, G
    SMITH, LG
    LESCOE, MK
    KANE, M
    EARABINO, C
    LIPFORD, J
    LINDBLOM, A
    TANNERGARD, P
    BOLLAG, RJ
    GODWIN, AR
    WARD, DC
    NORDENSKJOLD, M
    FISHEL, R
    KOLODNER, R
    LISKAY, RM
    [J]. NATURE, 1994, 368 (6468) : 258 - 261
  • [3] ISOLATION OF AN HMSH2-P160 HETERODIMER THAT RESTORES DNA MISMATCH REPAIR TO TUMOR-CELLS
    DRUMMOND, JT
    LI, GM
    LONGLEY, MJ
    MODRICH, P
    [J]. SCIENCE, 1995, 268 (5219) : 1909 - 1912
  • [4] THE HUMAN MUTATOR GENE HOMOLOG MSH2 AND ITS ASSOCIATION WITH HEREDITARY NONPOLYPOSIS COLON-CANCER
    FISHEL, R
    LESCOE, MK
    RAO, MRS
    COPELAND, NG
    JENKINS, NA
    GARBER, J
    KANE, M
    KOLODNER, R
    [J]. CELL, 1993, 75 (05) : 1027 - 1038
  • [5] HUGHES MJ, 1992, J BIOL CHEM, V267, P23876
  • [6] Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
    Konishi, M
    KikuchiYanoshita, R
    Tanaka, K
    Muraoka, M
    Onda, A
    Okumura, Y
    Kishi, N
    Iwama, T
    Mori, T
    Koike, M
    Ushio, K
    Chiba, M
    Nomizu, S
    Konishi, F
    Utsunomiya, J
    Miyaki, M
    [J]. GASTROENTEROLOGY, 1996, 111 (02) : 307 - 317
  • [7] MUTATIONS OF A MUTS HOMOLOG IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER
    LEACH, FS
    NICOLAIDES, NC
    PAPADOPOULOS, N
    LIU, B
    JEN, J
    PARSONS, R
    PELTOMAKI, P
    SISTONEN, P
    AALTONEN, LA
    NYSTROMLAHTI, M
    GUAN, XY
    ZHANG, J
    MELTZER, PS
    YU, JW
    KAO, FT
    CHEN, DJ
    CEROSALETTI, KM
    FOURNIER, REK
    TODD, S
    LEWIS, T
    LEACH, RJ
    NAYLOR, SL
    WEISSENBACH, J
    MECKLIN, JP
    JARVINEN, H
    PETERSEN, GM
    HAMILTON, SR
    GREEN, J
    JASS, J
    WATSON, P
    LYNCH, HT
    TRENT, JM
    DELACHAPELLE, A
    KINZLER, KW
    VOGELSTEIN, B
    [J]. CELL, 1993, 75 (06) : 1215 - 1225
  • [8] LYNCH HT, 1993, GASTROENTEROLOGY, V104, P1553
  • [9] Frameshift mutator mutations
    Malkhosyan, S
    Rampino, N
    Yamamoto, H
    Perucho, M
    [J]. NATURE, 1996, 382 (6591) : 499 - 500
  • [10] Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
    Marsischky, GT
    Filosi, N
    Kane, MF
    Kolodner, R
    [J]. GENES & DEVELOPMENT, 1996, 10 (04) : 407 - 420
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