SO2 conversion to sulfones: development and mechanistic insights of a sulfonylative Hiyama cross-coupling

被引：21

作者：

Adenot, Aurelien ^{[1
]}

Char, Joelle ^{[1
]}

von Wolff, Niklas ^{[1
]}

Lefevre, Guillaume ^{[1
]}

Anthore-Dalion, Lucile ^{[1
]}

Cantat, Thibault ^{[1
]}

机构：

[1] Univ Paris Saclay, CNRS, CEA, NIMBE,CEA Saclay, F-91191 Gif Sur Yvette, France

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 86期

基金：

欧洲研究理事会;

关键词：

SULFUR-DIOXIDE; REDUCTIVE ELIMINATION; ONE-POT; 3-COMPONENT; PALLADIUM; DABSO; COMPLEXES; LIGANDS;

D O I：

10.1039/c9cc06858a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Pd-catalyzed Hiyama cross-coupling reaction using SO2 is described. The use of silicon-based nucleophiles leads to the formation of allyl sulfones under mild conditions with a broad functional group tolerance. Control experiments coupled with DFT calculations shed light on the key steps of the reaction mechanism, revealing the crucial role of a transient sulfinate anion.

引用

页码：12924 / 12927

页数：4

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