Doppler variance imaging for three-dimensional retina and choroid angiography

被引：108

作者：

Yu, Lingfeng ^{[1
]}

Chen, Zhongping ^{[1
]}

机构：

[1] Univ Calif Irvine, Irvine Beckman Laser Inst, Dept Biomed Engn, Irvine, CA 92612 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2010年 / 15卷 / 01期

基金：

美国国家卫生研究院;

关键词：

ophthalmology; optical Doppler tomography; medical optics instrumentation; three-dimensional (3-D) image processing; OPTICAL COHERENCE TOMOGRAPHY; IN-VIVO; BLOOD-FLOW; HUMAN SKIN; VELOCITY; SPEED;

D O I：

10.1117/1.3302806

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate the use of Doppler variance (standard deviation ) imaging for 3-D in vivo angiography in the human eye. In addition to the regular optical Doppler tomography velocity and structural images, we use the variance of blood flow velocity to map the retina and choroid vessels. Variance imaging is subject to bulk motion artifacts as in phase-resolved Doppler imaging, and a histogram-based method is proposed for bulk-motion correction in variance imaging. Experiments were performed to demonstrate the effectiveness of the proposed method for 3-D vasculature imaging of human retina and choroid. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3302806]

引用

页数：4

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