共 209 条
Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft
被引:42
作者:

Cai, Qingjin
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机构:
Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Liao, Wanshan
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Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Xue, Fangchao
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h-index: 0
机构:
Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Wang, Xiaochen
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机构:
Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Zhou, Weiming
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h-index: 0
机构:
Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Li, Yanzhao
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h-index: 0
机构:
State Key Lab Trauma Burn & Combined Injury, Chongqing, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China

Zeng, Wen
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h-index: 0
机构:
Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China
State Key Lab Trauma Burn & Combined Injury, Chongqing, Peoples R China
Third Mil Med Univ, Southwest Hosp, Dept Neurol, Chongqing, Peoples R China Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China
机构:
[1] Third Mil Med Univ, Dept Cell Biol, Chongqing 400038, Peoples R China
[2] State Key Lab Trauma Burn & Combined Injury, Chongqing, Peoples R China
[3] Third Mil Med Univ, Southwest Hosp, Dept Neurol, Chongqing, Peoples R China
基金:
美国国家科学基金会;
关键词:
Tissue-engineered vascular grafts;
scaffold materials;
seed cells;
vascular endothelialization;
endothelial heterogeneity;
PLURIPOTENT STEM-CELLS;
SMOOTH-MUSCLE-CELLS;
PROGENITOR CELLS;
BLOOD-VESSELS;
FUNCTIONAL-CHARACTERIZATION;
CORD BLOOD;
SCAFFOLDS;
COLLAGEN;
HETEROGENEITY;
BYPASS;
D O I:
10.1016/j.bioactmat.2020.12.021
中图分类号:
R318 [生物医学工程];
学科分类号:
0831 ;
摘要:
Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs (<6 mm) after transplantation. Endothelialization of TEVGs is a key point to prevent thrombosis. Here, we discuss different types of endothelialization and different seed cells of tissue-engineered vascular grafts. Meanwhile, endothelial heterogeneity is also discussed. Based on it, we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths.
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收藏
页码:2557 / 2568
页数:12
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