Invasive candidiasis: A view to central nervous system infection

被引：3
|
作者：
Vigezzi, Cecilia [1 ,2 ,4 ,5 ]
Oscar Riera, Fernando [3 ,4 ,5 ]
Rodriguez, Emilse [1 ,2 ,4 ,5 ]
Alejandra Icely, Paula [1 ,2 ,4 ,5 ]
Soledad Miro, Maria [1 ,2 ,4 ,5 ]
Mauricio Figueredo, Carlos [1 ,2 ,4 ]
Pablo Caeiro, Juan [3 ,4 ]
Elena Sotomayor, Claudia [1 ,2 ,4 ,5 ]
机构：
[1] Dept Bioquim Clin, Lab Inmunidad Innata Patogenos Fung, Cordoba, Argentina
[2] Univ Nacl Cordoba, Fac Ciencias Quim, Ctr Invest Bioquim Clin & Inmunol, CIBIC CONICET, Cordoba, Argentina
[3] Sanatorio Allende, Serv Infectol, Cordoba, Argentina
[4] Hosp Privado Univ Cordoba, Serv Infectol, Cordoba, Argentina
[5] Res Grp Immunol & Mycol, Cordoba, Argentina
来源：
REVISTA ARGENTINA DE MICROBIOLOGIA | 2021年 / 53卷 / 02期
关键词：
Invasive candidias; Brain infection; beta-glucans; Dectin-1; CARDS; Genetic mutations; FUNGAL-INFECTION; HUMAN DECTIN-1; BRAIN; EPIDEMIOLOGY; DEFICIENCY; IMMUNITY; RECEPTOR; ALBICANS; CARD9;
D O I：
10.1016/j.ram.2020.06.003
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Candidemia is the most frequent invasive mycosis in hospitalized patients worldwide. Fungal infection in central nervous system is a life -threatening complication which aggravates patients' prognosis. This article summarizes relevant aspects on the clinical characteristics of this pathology, mechanisms of fungus invasion, local immune response to Candida albicans and the impact of genetic defects on innate immune receptors that increase susceptibility to the acquisition of this form of mycosis. (C) 2020 Asociacion Argentina de Microbiologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码：171 / 178
页数：8
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