Among the BPH-specific instruments available for assessing Quality of Life (QoL), no concensus has emerged on the concepts that should be measured, particularly for aspects of sexual life. In a cross-sectional study, 73 French and 44 English patients with an International Prostate Symptom Score (I-PSS) > 7 were asked to fill in this 89-item questionnaire. The level of interference of the symptoms with each aspect and the importance of the problem were reported by the patients. The aspects reported to be most affected and to be the most important were sleep, anxiety, mobility, leisure, daily activities, sexual activities and satisfaction with sexual relationship. French patients considered all sexual aspects of life more important than English patients. This study confirmed that QoL is an important outcome in BPH. The major concepts identified by the patients to be important included sexual ones.