Atypical Cushing's Syndrome in Dogs: Arguments For and Against

被引：21

作者：

Behrend, Ellen N. ^{[1
]}

Kennis, Robert ^{[1
]}

机构：

[1] Auburn Univ, Coll Vet Med, Dept Clin Sci, Auburn, AL 36849 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2010年 / 40卷 / 02期

关键词：

Hyperadrenocorticism; Sex hormones; Cushing's syndrome; Adrenal gland; Alopecia X; ARREST ALOPECIA-X; ADRENOCORTICOTROPIC HORMONE; CANINE HYPERADRENOCORTICISM; DEXAMETHASONE SUPPRESSION; ADRENAL-FUNCTION; SCREENING-TESTS; GROWTH-HORMONE; CANDIDATE GENE; SEX-HORMONES; DIAGNOSIS;

D O I：

10.1016/j.cvsm.2009.11.002

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In the past 5 to 10 years, much interest has arisen in the syndrome of occult hyperadrenocorticism. Patients with occult hyperadrenocorticism purportedly have many clinical signs and routine laboratory abnormalities suggestive of the presence of typical hyperadrenocorticism, or Cushing's syndrome (ie, hypercortisolism either due to a pituitary or adrenal tumor). However, the standard diagnostic tests-corticotropin (ACTH) stimulation and low-dose dexamethasone suppression tests-are normal. A theory has arisen that the clinical signs of occult hyperadrenocorticism are due to excess adrenal secretion of sex hormones rather than cortisol. The authors believe that the role of sex hormones has not been proven. The article reviews the evidence both for and against the importance of sex hormones in creating occult hyperadrenocorticism.

引用

页码：285 / +

页数：13

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