Quality of Life and Antiretroviral Therapy Adherence: A Cross-Sectional Study in Colombia

被引：0
作者：
Narvaez, Monica [1 ,2 ]
Lins-Kusterer, Liliane [1 ,2 ]
Valdelamar-Jimenez, Juliet [1 ,2 ]
Brites, Carlos [1 ,2 ,3 ]
机构：
[1] Univ Fed Bahia, Post Grad Program Med & Hlth PPgMS, Salvador, Brazil
[2] Univ Hosp Complex Prof Edgard St, Fed Univ Bahia, Res Lab Infect Dis LAPI, Salvador, Brazil
[3] Univ Fed Bahia, Post Grad Program Med & Hlth PPgMS, BR-40110060 Salvador, Brazil
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 2022年 / 38卷 / 08期
关键词：
HIV therapies; HIV clinical outcomes research; epidemiology; ART ADHERENCE; HIV; HIV/AIDS; TRANSMISSION; AIDS; PROGRESSION; DEPRESSION; RESISTANCE; INFECTION; ALCOHOL;
D O I：
10.1089/aid.2021.0233
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The introduction of highly active combined antiretroviral therapy (cART) has changed the management of HIV/AIDS, which is recognized as a chronic disease with relevant aspects, such as adherence and quality of life. This study aimed to compare clinical and demographic characteristics and health-related quality of life in people with adherence and non-adherence to cART. A cross-sectional study was carried out with 200 participants. The instruments used were the Adherence Follow-up Questionnaire, the Beck Depression Inventory-II, the 36-Item Short Form Health Survey and the WHOQOL-HIV BREF. Poisson regression was applied to obtain estimates of adjusted prevalence ratios (PRadj). Individuals lacking therapeutic support were more likely to be non-adherent than those with proper support (PR: 1.79). The health-related quality of life of individuals with non-adherence was 4% lower (PR = 0.96) in the general health domain than individuals with adherence. Non-adherence to cART was associated with lower quality of life in the general health domain and no therapeutic support.
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收藏
页码：660 / 669
页数：10
相关论文
共 74 条
[1]  
ACTG, 2001, ADH FOLLOW QUES
[2]  
Alonso, 2003, SPANISH VERSION SF 3
[3]  
ALONSO J, 1995, MED CLIN-BARCELONA, V104, P771
[4]   Correlates and predictors of adherence to highly active antiretroviral therapy: Overview of published literature [J].
Ammassari, A ;
Trotta, MP ;
Murri, R ;
Castelli, F ;
Narciso, P ;
Noto, P ;
Vecchiet, J ;
D'Arminio Monforte, A ;
Wu, AW ;
Antinori, A .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2002, 31 :S123-S127
[5]   Major depressive disorder and its association with adherence to antiretroviral therapy and quality of life: cross-sectional survey of people living with HIV/AIDS in Northwest Ethiopia [J].
Asrat, Biksegn ;
Lund, Crick ;
Ambaw, Fentie ;
Garman, Emily Claire ;
Schneider, Marguerite .
BMC PSYCHIATRY, 2020, 20 (01) :462
[6]  
Bada L., 2002, HLTH RELATED QUALITY
[7]   Non-adherence to highly active antiretroviral therapy predicts progression to AIDS [J].
Bangsberg, DR ;
Perry, S ;
Charlebois, ED ;
Clark, RA ;
Roberston, M ;
Zolopa, AR ;
Moss, A .
AIDS, 2001, 15 (09) :1181-1183
[8]   Alternatives for logistic regression in cross-sectional studies: An empirical comparison of models that directly estimate the prevalence ratio [J].
Aluísio JD Barros ;
Vânia N Hirakata .
BMC Medical Research Methodology, 3 (1) :1-13
[9]  
Beck AT., 1996, BDI-II: Beck Depression Inventory Manual. 2nd ed
[10]   Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil [J].
Betancur, Monica Narvaez ;
Lins, Liliane ;
de Oliveira, Irismar Reis ;
Brites, Carlos .
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, 2017, 21 (05) :507-514
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