Guided-wave optical biosensors

被引:109
作者
Passaro, Vittorio M. N.
Dell'Olio, Francesco
Casamassima, Biagio
De Leonardis, Francesco
机构
[1] Politecn Bari, Dipartimento Elettrotecn & Elettron, Photon Res Grp, I-70125 Bari, Italy
[2] Politecn Bari, Dipartimento Ingn Ambiente & Sviluppo Sostenibile, Photon Res Grp, I-74100 Taranto, Italy
关键词
biosensors; surface plasmon resonance; Mach-Zehnder interferometers; microdisk and microring; photonic technologies;
D O I
10.3390/s7040508
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.
引用
收藏
页码:508 / 536
页数:29
相关论文
共 46 条
[1]  
[Anonymous], BIOMEDICAL PHOTONICS
[2]   Silicon anti-resonant reflecting optical waveguides for sensor applications [J].
Benaissa, K ;
Nathan, A .
SENSORS AND ACTUATORS A-PHYSICAL, 1998, 65 (01) :33-44
[3]   A label-free affinity sensor with compensation of unspecific protein interaction by a highly sensitive integrated optical Mach-Zehnder interferometer on silicon [J].
Brosinger, F ;
Freimuth, H ;
Lacher, M ;
Ehrfeld, W ;
Gedig, E ;
Katerkamp, A ;
Spener, F ;
Cammann, K .
SENSORS AND ACTUATORS B-CHEMICAL, 1997, 44 (1-3) :350-355
[4]   Microfluidic sensor based on integrated optical hollow waveguides [J].
Campopiano, S ;
Bernini, R ;
Zeni, L ;
Sarro, PM .
OPTICS LETTERS, 2004, 29 (16) :1894-1896
[5]  
Cerussi A., 2003, BIOMEDICAL PHOTONICS
[6]   Biochemical sensors based on polymer microrings with sharp asymmetrical resonance [J].
Chao, CY ;
Guo, LJ .
APPLIED PHYSICS LETTERS, 2003, 83 (08) :1527-1529
[7]   Polymer microring resonators for biochemical sensing applications [J].
Chao, CY ;
Fung, W ;
Guo, LJ .
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2006, 12 (01) :134-142
[8]  
De Vos K., 2006, P S IEEE LEOS BEN CH, P213
[9]  
Dell'Olio F., 2006, P 11 INT M CHEM SENS, V27
[10]   Optical sensing by optimized silicon slot waveguides [J].
Dell'Olio, Francesco ;
Passaro, Vittorio M. N. .
OPTICS EXPRESS, 2007, 15 (08) :4977-4993