SYNTHESIS AND ANTIMICROBIAL PROPERTIES OF SOME THIAZOLE AND PYRIDINE DERIVATIVES

被引：0

作者：

Naghiyev, Farid N. ^{[1
]}

Asgarova, Ayten R. ^{[1
]}

Maharramov, Abel M. ^{[1
]}

Rahimova, Almaz G. ^{[1
]}

Akhundova, Mushkinaz A. ^{[1
]}

Mamedov, Ibrahim G. ^{[1
]}

机构：

[1] Baku State Univ, Dept Organ Chem, Z Khalilov 23, AZ-1148 Baku, Azerbaijan

来源：

NEW MATERIALS COMPOUNDS AND APPLICATIONS | 2020年 / 4卷 / 01期

关键词：

thiosemicarbazone; phenacyl bromide; thiazole; iminopyridine; NMR;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It was confirmed, that by condensation of thiosemicarbazide derivative of camphor with phenacyl bromide in ethanol and at the presence of piperidine, the corresponding thiazole derivatives are formed. By the interaction of camphor's thiosemicarbazide derivative with methyl ester of alpha-bromoacetic acid in the same reaction conditions, the corresponding thiazolidone derivative was synthesized. The way of synthesis of benzylamine the iminopyridine derivative by the one-pot three-component reaction of p-bromobenzylidene malononitrile with malononitrile has been developed. Synthesized pyridine derivative demonstrates high antimicrobial activity. Structures of all synthesized compounds confirmed by NMR spectroscopy.

引用

页码：5 / 9

页数：5

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