Isoform-selective phosphoinositide 3-kinase inhibitors induce apoptosis in chronic lymphocytic leukaemia cells

被引：8
作者：
de Frias, Merce [1 ]
Iglesias-Serret, Daniel [1 ]
Cosialls, Ana M. [1 ]
Gonzalez-Girones, Diana M. [1 ]
Perez-Perarnau, Alba [1 ]
Rubio-Patino, Camila [1 ]
Rueckle, Thomas [2 ,3 ]
Camps, Montserrat
Fernandez de Sevilla, Alberto [4 ]
de la Banda, Esmeralda [5 ]
Pons, Gabriel [1 ]
Gil, Joan [1 ]
机构：
[1] Univ Barcelona, Inst Invest Biomed Bellvitge, Dept Ciencies Fisiol 2, Barcelona, Spain
[2] Merck Serono SA, Res Ctr Geneva, Dept Chem, Geneva, Switzerland
[3] Merck Serono SA, Res Ctr Geneva, Dept Signal Transduct, Geneva, Switzerland
[4] IDIBELL Inst Catala Oncol, Dept Clin Hematol, Lhospitalet De Llobregat, Spain
[5] Bellvitge Hosp, Serv Hematol, IDIBELL, Barcelona, Spain
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2010年 / 150卷 / 01期
关键词：
chronic lymphocytic leukaemia; apoptosis; phosphoinositide; 3-kinase; THERAPY;
D O I：
10.1111/j.1365-2141.2010.08151.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：108 / 111
页数：4
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