Monoclonal Gammopathy of Renal Significance

被引:122
作者
Leung, Nelson [1 ,2 ]
Bridoux, Frank [4 ,5 ,6 ]
Nasr, Samih H. [3 ]
机构
[1] Mayo Clin, Div Nephrol, Rochester, MN USA
[2] Mayo Clin, Div Hypertens & Hematol, Rochester, MN USA
[3] Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA
[4] Univ Poitiers, Dept Nephrol, Poitiers, France
[5] Univ Poitiers, Ctr Invest Clin INSERM 1402, Ctr Reference Amylose & Autres Malad Depot Immuno, Ctr Hosp Univ, Poitiers, France
[6] Univ Limoges, CNRS, UMR7276, Limoges, France
关键词
CHAIN DEPOSITION DISEASE; UNDETERMINED SIGNIFICANCE MGUS; WALDENSTROM MACROGLOBULINEMIA; FANCONI-SYNDROME; NATURAL-HISTORY; MECHANISMS; BORTEZOMIB; CYCLOPHOSPHAMIDE; TRANSPLANTATION; GLOMERULOPATHY;
D O I
10.1056/NEJMra1810907
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Monoclonal Gammopathy of Renal Significance Monoclonal gammopathy of renal significance is a B-cell or plasma-cell clonal disorder that does not meet the criteria for cancer but produces a monoclonal immunoglobulin that leads to kidney injury or disease. This review discusses pathogenesis, evaluation, and management.
引用
收藏
页码:1931 / 1941
页数:11
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