Synthesis of novel 9,9-dimethyl-8,12-dihydro-9H-chromeno[3,2-e] [1,2,4]triazolo[1,5-c]pyrimidin-11(10H)-one derivatives

被引：6

作者：

Wang, Zhong-Xia ^{[1
]}

Li, Bei ^{[1
]}

Xing, Zheng ^{[2
]}

Chen, Li-Zhuang ^{[1
]}

Han, Guang-Fan ^{[1
,2
]}

机构：

[1] Jiangsu Univ Sci & Technol, Sch Environm & Chem Engn, Dept Appl Chem, Zhenjiang 212003, Jiangsu, Peoples R China

[2] Zhenjiang Coll, Zhenjiang 212000, Jiangsu, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2014年 / 08期

基金：

中国国家自然科学基金;

关键词：

chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-11(10H)-one; formimidate; chromeno[2,3-d]pyrimidine; AGENTS;

D O I：

10.3184/174751914X14053476598397

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel 9,9-dimethyl-8,12-dihydro-9H-chromeno[3,2-e][1,2,4] triazolo[1,5-c]pyrimidin-11(10H)-one derivatives were synthesised by the reactions of triethyl orthoformate or aromatic aldehydes with chromeno[2,3-d]pyrimidine derivatives, which were prepared by the reactions of hydrazine monohydrate and formimidate derivatives. Formimidate were synthesised by the reactions of 2-amino-7,7-dimethyl-5-oxo-4-aryl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile derivatives and triethyl orthoformate. The structures of 12-(4-methoxyphenyl)-9,9-dimethyl-8,12-dihydro-9H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-11(10H)-one was determined by single crystal X-ray diffraction analysis.

引用

页码：480 / 485

页数：6

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