Effect of Aerobic Exercise on Peak Oxygen Consumption, VE/VCO2 Slope, and Health-Related Quality of Life in Patients with Heart Failure with Preserved Left Ventricular Ejection Fraction: a Systematic Review and Meta-Analysis

被引：23

作者：

Gomes-Neto, Mansueto ^{[1
,2
,3
,4
]}

Duraes, Andre Rodrigues ^{[2
]}

Rocha Conceicao, Lino Sergio ^{[4
,12
]}

Roever, Leonardo ^{[5
]}

Liu, Tong ^{[6
,7
]}

Tse, Gary ^{[8
]}

Biondi-Zoccai, Giuseppe ^{[9
]}

Barbosa Goes, Ana Lucia ^{[3
]}

Nogueira Alves, Iura Gonzalez ^{[3
]}

Ellingsen, Oyvind ^{[10
,11
]}

Carvalho, Vitor Oliveira ^{[4
,12
]}

机构：

[1] Fed Univ Bahia UFBA, Inst Ciencias Saude, Phys Therapy Dept, Av Reitor Miguel Calmon S-N Vale Canela Salvador, BR-40110100 Salvador, BA, Brazil

[2] Univ Fed Bahia, Programa Posgrad Med & Saude, Salvador, BA, Brazil

[3] Univ Fed Bahia, Physiotherapy Res Grp, Salvador, BA, Brazil

[4] GREAT Grp GRp Estudos ATividade Fis, Sao Paulo, Brazil

[5] Univ Fed Uberlandia, Dept Clin Res, Uberlandia, MG, Brazil

[6] Tianjin Med Univ, Tianjin Key Lab Ion Mol Funct Cardiovasc Dis, Dept Cardiol, Tianjin Inst Cardiol,Hosp 2, Tianjin, Peoples R China

[7] Chinese Univ Hong Kong, Shenzhen Res Inst, Hong Kong, Peoples R China

[8] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Latina, Italy

[9] Mediterranea Cardioctr, Naples, Italy

[10] Norwegian Univ Sci & Technol, Dept Circulat & Med Imaging, KG Jebsen Ctr Exercise Med, Fac Med & Hlth Sci, Trondheim, Norway

[11] St Olavs Hosp, Trondheim Univ Hosp, Dept Cardiol, Trondheim, Norway

[12] Fed Univ Sergipe UFS, Phys Therapy Dept, Aracaju, SE, Brazil

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2019年 / 21卷 / 11期

关键词：

Aerobic exercise; Heart failure; Left ventricular ejection fraction; CLINICAL-OUTCOMES; OLDER PATIENTS; DETERMINANTS; ASSOCIATION; INTOLERANCE; TRIALS; SCORE; CARE; VO2;

D O I：

10.1007/s11883-019-0806-6

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Purpose of Review The aim of this study was to determine the effects of aerobic exercise on peak oxygen uptake (peak VO2), minute ventilation/carbon dioxide production (VE/VCO2 slope), and health-related quality of life (HRQoL) among patients with heart failure (HF) and preserved ejection fraction (HFpEF). Recent Findings We conducted a Cochrane Library, MEDLINE/PubMed, Physiotherapy Evidence Database, and SciELO search (from 1985 to May 2019) for randomized controlled trials that evaluated the effects of aerobic exercise in HFpEF patients. We calculated the mean differences (MD) and 95% confidence interval (CI). Ten intervention studies were included providing a total of 399 patients. Compared with control, aerobic exercise resulted in improvement in peak VO2 MD 1.9 mL kg(-1) min(-1) (95% CI 1.3 to 2.5; N = 314) and HRQoL measured by Minnesota Living with Heart Failure MD 5.4 (95% CI - 10.5 to - 0.2; N = 256). No significant difference in VE/VCO2 slope was found between participants in the aerobic exercise group and the control group. The quality of evidence for peak VO2 and HRQoL was assessed as being moderate. Aerobic exercise moderately improves peak VO2 and HRQoL and should be considered a strategy of rehabilitation of HFpEF individuals.

引用

页数：8