Non-enzymatic sensing of glucose using a glassy carbon electrode modified with gold nanoparticles coated with polyethyleneimine and 3-aminophenylboronic acid

被引：41

作者：

Ciftci, Hakan ^{[1
]}

Alver, Erol ^{[2
]}

Celik, Filiz ^{[1
]}

Metin, Aysegul U. ^{[3
]}

Tamer, Ugur ^{[4
]}

机构：

[1] Kirikkale Univ, Dept Chem & Chem Proc Technol, Kirikkale Vocat High Sch, TR-71450 Kirikkale, Turkey

[2] Hitit Univ, Fac Engn, Dept Chem Engn, TR-19030 Corum, Turkey

[3] Kirikkale Univ, Fac Arts & Sci, Dept Chem, TR-71450 Kirikkale, Turkey

[4] Gazi Univ, Fac Pharm, Dept Analyt Chem, TR-06330 Ankara, Turkey

来源：

MICROCHIMICA ACTA | 2016年 / 183卷 / 04期

关键词：

Molecular recognition; Nanomaterial; Colloidal gold; Zeta potential; Potentiometry; Dynamic light scattering; FTIR; Transmission electron microscopy; GRAPHENE OXIDE; POTENTIOMETRIC DETECTION; SILVER NANOPARTICLES; BORONIC ACID; SENSOR; NANOCOMPOSITES; RECOGNITION; SACCHARIDES; FACILE; FILM;

D O I：

10.1007/s00604-016-1782-y

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A non-enzymatic electrochemical method was developed for sensing glucose by using a glassy carbon electrode modified with 3-aminophenylboronic acid (APBA) immobilized on polyethyleneimine (PEI)-coated gold nanoparticles. The modified electrode was characterized by TEM, zeta potential measurements and UV-Vis spectroscopy. Its analytical performance was evaluated in pH 9 solution by potentiometry. The respective calibration plot, established at open circuit potential (vs. Ag/AgCl) covers the 0.5-50 mM glucose concentration range, which makes it suitable for blood glucose assays. The detection limit is 0.025 mM, and no interference is caused by ascorbic acid, dopamine, and uric acid. Effects of other carbohydrates such as fructose, galactose and saccharose were also investigated. The electrode was used to determine glucose in human serum samples and the results agreed well with those obtained with commercial amperometric enzymatic sensors.

引用

页码：1479 / 1486

页数：8

共 33 条

[1] High ionic strength glucose-sensing photonic crystal [J].

Alexeev, VL ;

Sharma, AC ;

Goponenko, AV ;

Das, S ;

Lednev, IK ;

Wilcox, CS ;

Finegold, DN ;

Asher, SA .

ANALYTICAL CHEMISTRY, 2003, 75 (10) :2316-2323

[2] The nanocomposite of PtPd nanoparticles/onion-like mesoporous carbon vesicle for nonenzymatic amperometric sensing of glucose [J].

Bo, Xiangjie ;

Bai, Jing ;

Yang, Li ;

Guo, Liping .

SENSORS AND ACTUATORS B-CHEMICAL, 2011, 157 (02) :662-668

[3] Size-dependent transfection efficiency of PEI-coated gold nanoparticles [J].

Cebrian, Virginia ;

Martin-Saavedra, Francisco ;

Yaguee, Clara ;

Arruebo, Manuel ;

Santamaria, Jesus ;

Vilaboa, Nuria .

ACTA BIOMATERIALIA, 2011, 7 (10) :3645-3655

[4] Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid [J].

Chen, Xiaomei ;

Wu, Genghuang ;

Cai, Zhixiong ;

Oyama, Munetaka ;

Chen, Xi .

MICROCHIMICA ACTA, 2014, 181 (7-8) :689-705

[5] An enzyme free potentiometric detection of glucose based on a conducting polymer poly (3-aminophenyl boronic acid-co-3-octylthiophene) [J].

Ciftci, Hakan ;

Tamer, Ugur ;

Sen Teker, Mine ;

Pekmez, Nuran Ozcicek .

ELECTROCHIMICA ACTA, 2013, 90 :358-365

[6] Functional gold nanorod particles on conducting polymer poly(3-octylthiophene) as non-enzymatic glucose sensor [J].

Ciftci, Hakan ;

Tamer, Ugur .

REACTIVE & FUNCTIONAL POLYMERS, 2012, 72 (02) :127-132

[7] Electrochemical glucose sensor based on one-step construction of gold nanoparticle-chitosan composite film [J].

Feng, Duan ;

Wang, Fang ;

Chen, Zilin .

SENSORS AND ACTUATORS B-CHEMICAL, 2009, 138 (02) :539-544

[8] Human sulfite oxidase electrochemistry on gold nanoparticles modified electrode [J].

Frasca, Stefano ;

Rojas, Oscar ;

Salewski, Johannes ;

Neumann, Bettina ;

Stiba, Konstanze ;

Weidinger, Inez M. ;

Tiersch, Brigitte ;

Leimkuehler, Silke ;

Koetz, Joachim ;

Wollenberger, Ulla .

BIOELECTROCHEMISTRY, 2012, 87 :33-41

[9] One-Step Electrochemical Synthesis of PtNi Nanoparticle-Graphene Nanocomposites for Nonenzynnatic Amperometric Glucose Detection [J].

Gao, Hongcai ;

Xiao, Fei ;

Ching, Chi Bun ;

Duan, Hongwei .

ACS APPLIED MATERIALS & INTERFACES, 2011, 3 (08) :3049-3057

[10] Polymers effects on synthesis of AuNPs, and Au/Ag nanoalloys: Indirectly generated AuNPs and versatile sensing applications including anti-leukemic agent [J].

Jahan, Shanaz ;

Mansoor, Farrukh ;

Kanwal, Shamsa .

BIOSENSORS & BIOELECTRONICS, 2014, 53 :51-57

← 1 2 3 4 →