3D additive-manufactured nanocomposite magnetic scaffolds: Effect of the application mode of a time-dependent magnetic field on hMSCs behavior

被引：70

作者：

D'Amora, Ugo ^{[1
]}

Russo, Teresa ^{[1
]}

Gloria, Antonio ^{[1
]}

Rivieccio, Virginia ^{[2
]}

D'Anto, Vincenzo ^{[3
,4
]}

Negri, Giacomo ^{[2
]}

Ambrosio, Luigi ^{[1
]}

De Santis, Roberto ^{[1
]}

机构：

[1] CNR, Inst Polymers Composites & Biomat, Vle JF Kennedy,54 Mostra Oltremare,Pad 20, I-80125 Naples, Italy

[2] Villa Betania Evangel Hosp, Naples, Italy

[3] Univ Naples Federico II, Dept Neurosci Reprod Sci & Oral Sci, Naples, Italy

[4] Bambino Gesu Pediat Hosp, IRCCS, Unit Dent, Rome, Italy

来源：

BIOACTIVE MATERIALS | 2017年 / 2卷 / 03期

关键词：

Additive manufacturing; Scaffold; Magnetic field; Cell-material interaction; PULSED ELECTROMAGNETIC-FIELDS; BONE-FORMATION; SAOS-2; CELLS; STIMULATION; DIFFERENTIATION; HYDROXYAPATITE; OSTEOBLASTS; INHIBITION; DESIGN;

D O I：

10.1016/j.bioactmat.2017.04.003

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Over the past few years, the influence of static or dynamic magnetic fields on biological systems has become a topic of considerable interest. Magnetism has recently been implicated to play significant roles in the regulation of cell responses and, for this reason, it is revolutionizing many aspects of healthcare, also suggesting new opportunities in tissue engineering. The aim of the present study was to analyze the effect of the application mode of a time-dependent magnetic field on the behavior of human mesenchymal stem cells (hMSCs) seeded on 3D additive-manufactured poly(epsilon-caprolactone)/iron-doped hydroxyapatite (PCL/FeHA) nanocomposite scaffolds. (C) 2017 The Authors. Production and hosting by Elsevier B.V.

引用

页码：138 / 145

页数：8

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