Dosimetric properties of Gafchromic® EBT films in monoenergetic medical ion beams

被引:70
作者
Martisikova, Maria [1 ]
Jaekel, Oliver [1 ,2 ]
机构
[1] German Canc Res Ctr, Dept Med Phys Radiat Oncol, D-69120 Heidelberg, Germany
[2] Univ Klinikum Heidelberg, HIT, D-69120 Heidelberg, Germany
关键词
PROTON; VERIFICATION; DEPENDENCE; PHOTON; SYSTEM; RANGE;
D O I
10.1088/0031-9155/55/13/011
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
For quality assurance measurements in radiotherapy with scanned ion beams, such as beam profile measurements and dosimetrical verification of patient plans, high spatial accuracy is required. We investigated the Gafchromic EBT film, which is the ancestor of the currently available EBT2 film, for this purpose. The excellent spatial resolution and improvements in sensitivity as compared to older types of radiochromic films make it a suitable candidate. In this contribution a study of the dose-response relation for monoenergetic beams (plateau), based on the absolute dose, is presented. We found the film response to be comparable for protons and photons. For carbon ions we observed a decrease in the darkening efficiency of about 30% with respect to photons. This effect is likely to be caused by the ion track structure. We did not find any dependence of the relative efficiency on the applied dose and energy over typical ranges used in ion beam therapy. Furthermore, it is shown that overlaps of ion tracks are not an issue for EBT film dosimetry in medical ion beams. The above findings enable the use of EBT films calibrated in a beam of a particular ion type for dose measurements at any other dose and energy. The uncertainty of the film darkening determination in ion beams is also discussed.
引用
收藏
页码:3741 / 3751
页数:11
相关论文
共 27 条
[21]   Analysis of uncertainties in Gafchromic® EBT film dosimetry of photon beams [J].
Martisikova, Maria ;
Ackermann, Benjamin ;
Jaekel, Oliver .
PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (24) :7013-7027
[22]   Experimental validation of a Monte Carlo proton therapy nozzle model incorporating magnetically steered protons [J].
Peterson, S. W. ;
Polf, J. ;
Bues, M. ;
Ciangaru, G. ;
Archambault, L. ;
Beddar, S. ;
Smith, A. .
PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (10) :3217-3229
[23]   Radiochromic film dosimetry of a low energy proton beam [J].
Piermattei, A ;
Miceli, R ;
Azario, L ;
Fidanzio, A ;
delle Canne, S ;
De Angelis, C ;
Onori, S ;
Pacilio, M ;
Petetti, E ;
Raffaele, L ;
Sabini, MG .
MEDICAL PHYSICS, 2000, 27 (07) :1655-1660
[24]   Experimental investigations of the response of films to heavy-ion irradiation [J].
Spielberger, B ;
Scholz, M ;
Krämer, M ;
Kraft, G .
PHYSICS IN MEDICINE AND BIOLOGY, 2001, 46 (11) :2889-2897
[25]   Dosimetry techniques for narrow proton beam radiosurgery [J].
Vatnitsky, SM ;
Miller, DW ;
Moyers, MF ;
Levy, RP ;
Schulte, RW ;
Slater, JD ;
Slater, JM .
PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (11) :2789-2801
[26]   Radiochromic film dosimetry for verification of dose distributions delivered with proton-beam radiosurgery [J].
Vatnitsky, SM ;
Schulte, RWM ;
Galindo, R ;
Meinass, HJ ;
Miller, DW .
PHYSICS IN MEDICINE AND BIOLOGY, 1997, 42 (10) :1887-1898
[27]   Radiochromic film dosimetry for clinical proton beams [J].
Vatnitsky, SM .
APPLIED RADIATION AND ISOTOPES, 1997, 48 (05) :643-651