Expression pattern of the C-elegans p21-activated protein kinase, CePAK

被引：7
|
作者：
Iino, Y [1 ]
Yamamoto, M [1 ]
机构：
[1] Univ Tokyo, Grad Sch Sci, Dept Biochem & Biophys, Bunkyo Ku, Tokyo 1130033, Japan
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1998年 / 245卷 / 01期
关键词：
D O I：
10.1006/bbrc.1998.8380
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The C. elegans p21-activated protein kinase (CePAK) has a high amino-acid sequence similarity to mammalian PAKs. Tissue specificity of the expression of CePAK was examined using lacZ and GFP reporters. This analysis indicated that CePAK is expressed mainly in pharyngeal muscles, the CAN neurons, and motor neurons in the ventral nerve cord, as well as several cells in the tail region and the distal tip cells. The CePAK::GFP fusion protein was preferentially localized to the cell surface in pharyngeal muscles. (C) 1998 Academic Press.
引用
收藏
页码：177 / 184
页数：8
相关论文
共 50 条
  • [1] Increased expression of p21-activated kinase in adenomyosis
    Kim, So Ra
    Kim, Sung Hoon
    Lee, Hoi Woul
    Chae, Hee Dong
    Kim, Chung-Hoon
    Kang, Byung Moon
    FERTILITY AND STERILITY, 2010, 94 (03) : 1125 - 1128
  • [2] Expression of P21-activated protein kinase γ-PAK in mammalian cells.
    Huang, ZD
    Traugh, JA
    FASEB JOURNAL, 1999, 13 (07): : A1578 - A1578
  • [3] Mitogen-activated protein kinase pathways in C-elegans
    Hisamoto, N
    Sakamoto, R
    Matsumoto, K
    GENOME SCIENCE: TOWARDS A NEW PARADIGM?, 2002, 1246 : 91 - 99
  • [4] p21-Activated kinase 5: A pleiotropic kinase
    Wen, Yi-Yang
    Wang, Xiao-Xia
    Pei, Dong-Sheng
    Zheng, Jun-Nian
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (24) : 6636 - 6639
  • [5] Protein kinase C isotypes in C-elegans
    Tabuse, Y
    JOURNAL OF BIOCHEMISTRY, 2002, 132 (04): : 519 - 522
  • [6] p21-activated protein kinase: a crucial component of morphological signaling?
    Daniels, RH
    Bokoch, GM
    TRENDS IN BIOCHEMICAL SCIENCES, 1999, 24 (09) : 350 - 355
  • [7] The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation
    Chen, WN
    Chen, S
    Yap, SF
    Lim, L
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (42) : 26362 - 26368
  • [8] EXPRESSION AND REGULATION OF P21-ACTIVATED KINASE IN HUMAN ENDOMETRIUM AND ENDOMETRIOSIS
    Kim, S. H.
    Chae, H. D.
    Kim, C. H.
    Kang, B. M.
    FERTILITY AND STERILITY, 2012, 98 (03) : S215 - S216
  • [9] Structural insights into autoactivation mechanism of p21-activated protein kinase
    Wang, Zhi-Xin
    Wang, Jue
    Wu, Jia-Wei
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2011, 67 : C789 - C789
  • [10] Structural Insights into the Autoactivation Mechanism of p21-Activated Protein Kinase
    Wang, Jue
    Wu, Jia-Wei
    Wang, Zhi-Xin
    STRUCTURE, 2011, 19 (12) : 1752 - 1761
12345