A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery

被引：48
|
作者：
Zeng, Xiaodong [1 ,2 ,3 ]
Xie, Liru [1 ]
Chen, Deliang [4 ]
Li, Shanshan [2 ]
Nong, Jinxia [2 ]
Wang, Bo [1 ]
Tang, Lin [2 ]
Li, Qianqian [2 ]
Li, Yang [2 ]
Deng, Zixin [2 ,3 ]
Hong, Xuechuan [2 ,3 ,5 ]
Wu, Mingfu [1 ,3 ]
Xiao, Yuling [2 ,3 ]
机构：
[1] Huazhong Univ Sci & Technol, State Key Lab Virol, Dept Gynecol, Canc Biol Res Ctr,Tongji Hosp,Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
[2] Wuhan Univ, Hubei Prov Engn & Technol Res Ctr Fluorinated Pha, Key Lab Combinatorial Biosynth & Drug Discovery M, Sch Pharmaceut Sci, Wuhan 430071, Hubei, Peoples R China
[3] Tibet Univ, Coll Med, Innovat Ctr Tradit Tibetan Med Modernizat & Qual, Lhasa 850000, Xizang, Peoples R China
[4] Gannan Normal Univ, Chem & Chem Engn Coll, Jiangxi Key Lab Organopharmaceut Chem, Ganzhou 341000, Jiangxi, Peoples R China
[5] Chengdu Univ Tradit Chinese Med, Innovat Inst Chinese Med & Pharm, Chengdu 611137, Sichuan, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 95期
关键词：
IN-VIVO; FLUOROPHORES; CANCER; BREAKTHROUGH; DESIGN; DOTS;
D O I：
10.1039/c9cc07694h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel bright near-infrared II (NIR-II, 1000-1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chemically induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated.
引用
收藏
页码：14287 / 14290
页数：4
相关论文
共 50 条
  • [41] Lighting Up NIR-II Fluorescence in Vivo: An Activable Probe for Noninvasive Hydroxyl Radical Imaging
    Feng, Wenqi
    Zhang, Yuying
    Li, Zhen
    Zhai, Shuyang
    Lv, Weijie
    Liu, Zhihong
    ANALYTICAL CHEMISTRY, 2019, 91 (24) : 15757 - 15762
  • [42] Conjugated Polymer Nanoparticles with Absorption beyond 1000 nm for NIR-II Fluorescence Imaging System Guided NIR-II Photothermal Therapy
    Song, Xingwen
    Lu, Xiaomei
    Sun, Bo
    Zhang, Hua
    Sun, Pengfei
    Miao, Han
    Fan, Quli
    Huang, Wei
    ACS APPLIED POLYMER MATERIALS, 2020, 2 (10) : 4171 - 4179
  • [43] An oral ratiometric NIR-II fluorescent probe for reliable monitoring of gastrointestinal diseases in vivo
    Li, Tuanwei
    Cao, Kaili
    Yang, Xiaohu
    Liu, Yongyang
    Wang, Xingyu
    Wu, Feng
    Chen, Guangcun
    Wang, Qiangbin
    BIOMATERIALS, 2023, 293
  • [44] Bright, Magnetic NIR-II Quantum Dot Probe for Sensitive Dual-Modality Imaging and Intensive Combination Therapy of Cancer
    Li, Yingying
    Zhang, Peisen
    Tang, Wen
    McHugh, Kevin J.
    Kershaw, Stephen V.
    Jiao, Mingxia
    Huang, Xiaodan
    Kalytchuk, Sergii
    Perkinson, Collin F.
    Yue, Saisai
    Qiao, Yuanyuan
    Zhu, Lichong
    Jing, Lihong
    Gao, Mingyuan
    Han, Buxing
    ACS NANO, 2022, 16 (05) : 8076 - 8094
  • [45] Multifunctional Nanotheranostic Agent for NIR-II Imaging-Guided Synergetic Photothermal/Photodynamic Therapy
    Li, Tuanwei
    Liu, Le
    Xu, Pengping
    Yuan, Pan
    Tian, Youliang
    Cheng, Quan
    Yan, Lifeng
    ADVANCED THERAPEUTICS, 2021, 4 (03)
  • [46] Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window
    Zhang, Xiaofan
    Li, Xiaohua
    Shi, Wen
    Ma, Huimin
    CHEMICAL COMMUNICATIONS, 2021, 57 (66) : 8174 - 8177
  • [47] An APN-Activated Chemiluminescent Probe for Image-Guided Surgery of Malignant Tumors
    Liu, Yinghua
    Zeng, Jianfeng
    Li, Qing
    Miao, Minqian
    Song, Zhuorun
    Zhao, Min
    Miao, Qingqing
    Gao, Mingyuan
    ADVANCED OPTICAL MATERIALS, 2022, 10 (14)
  • [48] Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics
    Roy, Shubham
    Bag, Neelanjana
    Bardhan, Souravi
    Hasan, Ikram
    Guo, Bing
    ADVANCED DRUG DELIVERY REVIEWS, 2023, 197
  • [49] An Activatable NIR-II Fluorescent Reporter for In Vivo Imaging of Amyloid-β Plaques
    Miao, Jia
    Miao, Minqian
    Jiang, Yue
    Zhao, Min
    Li, Qing
    Zhang, Yuan
    An, Yi
    Pu, Kanyi
    Miao, Qingqing
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 62 (07)
  • [50] Multiplexed NIR-II Probes for Lymph Node-Invaded Cancer Detection and Imaging-Guided Surgery
    Tian, Rui
    Ma, Huilong
    Zhu, Shoujun
    Lau, Joseph
    Ma, Rui
    Liu, Yijing
    Lin, Lisen
    Chandra, Swati
    Wang, Sheng
    Zhu, Xingfu
    Deng, Hongzhang
    Niu, Gang
    Zhang, Mingxi
    Antaris, Alexander L.
    Hettie, Kenneth S.
    Yang, Bai
    Liang, Yongye
    Chen, Xiaoyuan
    ADVANCED MATERIALS, 2020, 32 (11)
12345