Special considerations for the treatment of chronic kidney disease in the elderly

被引：6

作者：

Corsonello, Andrea ^{[1
]}

Fusco, Sergio ^{[1
]}

Bustacchini, Silvia ^{[2
]}

Chiatti, Carlos ^{[2
]}

Moresi, Raffaella ^{[2
]}

Bonfigli, Anna Rita ^{[2
]}

Di Stefano, Giuseppina ^{[2
]}

Lattanzio, Fabrizia ^{[2
]}

机构：

[1] Res Hosp Cosenza, Italian Natl Res Ctr Aging, Unit Geriatr Pharmacoepidemiol, I-87100 Cosenza, Italy

[2] Italian Natl Res Ctr Aging, Sci Direct, Ancona, Italy

来源：

EXPERT REVIEW OF CLINICAL PHARMACOLOGY | 2016年 / 9卷 / 05期

关键词：

osteoporosis; Chronic kidney disease; comprehensive geriatric assessment; anemia; hypertension; diabetes; rehabilitation; renal replacement therapy; acidosis; albuminuria; CLINICAL-PRACTICE GUIDELINE; STAGE RENAL-DISEASE; GLOMERULAR-FILTRATION-RATE; TYPE-2; DIABETES-MELLITUS; GLP-1 RECEPTOR AGONISTS; BLOOD-PRESSURE; OLDER-ADULTS; CARDIOVASCULAR EVENTS; DECISION-MAKING; CONSERVATIVE MANAGEMENT;

D O I：

10.1586/17512433.2016.1155448

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally, physical exercise and rehabilitation interventions also represents a promising therapeutic strategy.

引用

页码：727 / 737

页数：11

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