Cyanogen Bromide as Dehydrosulfurizing Agent for the Synthesis of Nβ-Fmoc-Amino Alkyl Isonitriles from Nβ-Fmoc-Amino Alkyl Thioformamides

被引：2

作者：

Vishwanatha, T. M. ^{[1
]}

Hemantha, H. P. ^{[1
]}

Sureshbabu, V. V. ^{[1
]}

机构：

[1] Bangalore Univ, Peptide Res Lab, Dept Studies Chem, Bangalore 560001, Karnataka, India

来源：

SYNLETT | 2010年 / 07期

关键词：

N-beta-Fmoc-amino alkyl thioformamides; isonitriles; dehydrosulfurization; cyanogen bromide; 4-COMPONENT REACTION; NATURAL-PRODUCTS; BUILDING-BLOCKS; ISOCYANIDES; DERIVATIVES; ACIDS; ISOTHIOCYANATES; CONDENSATION; CHEMISTRY; MIMETICS;

D O I：

10.1055/s-0029-1219583

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetically useful N-beta-Fmoc amino alkyl isonitriles are prepared conveniently from N-beta-Fmoc amino alkyl thioformamides via a cyanogen bromide mediated dehydrosulfurization. The reaction is fast, clean, and yields are good.

引用

页码：1096 / 1100

页数：5

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