Rheumatic Manifestations in Acromegaly

被引：0

作者：

Patschan, Susann ^{[1
]}

Patschan, Daniel ^{[2
]}

Raddatz, Dirk ^{[3
]}

Gollisch, Katja ^{[3
]}

机构：

[1] Univ Hosp Gottingen, Clin Nephrol & Rheumatol, Robert Koch Str 40, D-37075 Gottingen, Germany

[2] Med Hsch Brandenburg Theodor Fontane, Klin Kardiol Pulmol Angiol & Nephrol, Brandenburg, Germany

[3] Univ Hosp Gottingen, Clin Gastroenterol, Gottingen, Germany

来源：

AKTUELLE RHEUMATOLOGIE | 2018年 / 43卷 / 03期

关键词：

acromegaly; rheumatoid arthritis; bone disease; BONE-MINERAL DENSITY; DISEASE-ACTIVITY; ARTHROPATHY; OSTEOARTHRITIS; REVERSIBILITY; THERAPY;

D O I：

10.1055/s-0043-122675

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acromegaly is a rare disease, which mostly results from pituitary overproduction of growth hormone (GH) followed by uncontrolled release of insulin-like growth factor-1 (IGF-1). The latter induces organ damage and metabolic disturbances including organomegaly, arterial hypertension and diabetes mellitus. Cardiovascular diseases are the most common cause of death in acromegaly patients. Individuals also frequently suffer from rheumatic disorders including large-joint disease, spinal affection and carpal tunnel syndrome. The most important therapeutic measure is to normalise GH/IGF-1 levels. Nevertheless, some rheumatic manifestations may not necessarily resolve since joint and spine affection are often irreversible in nature.

引用

页码：235 / 239

页数：5

共 50 条

[31] Assessment of nutritional deficiency manifestations in patients with rheumatic diseases [J].

Elshebini, Emad ;

Elsawah, Hozaifa ;

Fathy, Taghreed ;

Abdelrahman, Sherry ;

Youssif, Omar ;

Ashraf, Soaad ;

Mourad, Nibal ;

Elnaggar, Mohamed ;

Elshebiny, Ahmed ;

Daif, Shymaa ;

Zahran, Enas .

EGYPTIAN RHEUMATOLOGIST, 2021, 43 (02) :167-171

[32] Alterations in body composition in acromegaly [J].

Katznelson, Laurence .

PITUITARY, 2009, 12 (02) :136-142

[33] Bone and Joint Disorders in Acromegaly [J].

Claessen, Kim M. J. A. ;

Mazziotti, Gherardo ;

Biermasz, Nienke R. ;

Giustina, Andrea .

NEUROENDOCRINOLOGY, 2016, 103 (01) :86-95

[34] Understanding the effect of acromegaly on the human skeleton [J].

Bima, C. ;

Chiloiro, S. ;

Mormando, M. ;

Piacentini, S. ;

Bracaccia, E. ;

Giampietro, A. ;

Tartaglione, L. ;

Bianchi, A. ;

De Marinis, L. .

EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, 2016, 11 (03) :263-270

[35] The “rheumatic lung” in computed tomography: radiological manifestations of rheumatoid arthritis [J].

Maier S. ;

Bonella F. ;

Kühl H. .

Der Pneumologe, 2018, 15 (6) :419-427

[36] Cardiovascular manifestations in patients with rheumatic diseases and COVID-19 [J].

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[37] Is every joint symptom related to acromegaly? [J].

Gonca Örük ;

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Mehmet Argın ;

Mustafa Özmen .

Endocrine, 2013, 43 :404-411

[38] Is every joint symptom related to acromegaly? [J].

Oruk, Gonca ;

Tarhan, Figen ;

Argin, Mehmet ;

Ozmen, Mustafa .

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[39] Musculoskeletal complications of acromegaly: what radiologists should know about early manifestations [J].

Tagliafico, A. ;

Resmini, E. ;

Ferone, D. ;

Martinoli, C. .

RADIOLOGIA MEDICA, 2011, 116 (05) :781-792

[40] Acromegaly versus hypogonadism: Bone fragility and evaluation [J].

Sorohan, Madalina Cristina ;

Baciu, Ionela Florina ;

Galoiu, Simona Andreea ;

Niculescu, Dan Alexandru ;

Caragheorgheopol, Andra ;

Iordachescu, Carmen Nicoleta ;

Poiana, Catalina .

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