Asymmetry of Modifications of the Electrical Activity of the Rat Cortex Induced by Intraventricular Injections of Thyrotropin-Releasing Hormone

被引：0
作者：
Lobasyuk, B. A. [1 ]
Andronati, S. A. [2 ]
Kostenko, S. V. [2 ]
Mazurov, A. A. [2 ]
Godlevskii, L. S. [3 ]
机构：
[1] Mechnikov Odessa Natl Univ, Odessa, Ukraine
[2] Natl Acad Sci Ukraine, Bogatskii Physicochem Inst, Odessa, Ukraine
[3] Odessa State Med Univ, Minist Publ Hlth Ukraine, Odessa, Ukraine
来源：
NEUROPHYSIOLOGY | 2004年 / 36卷 / 5-6期
关键词：
thyrotropin-releasing hormone; antidepressive effects; electrocorticogram; functional interhemisphere asymmetry;
D O I：
10.1007/s11062-005-0028-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We studied modifications in the mass electrical activity of the cortex (ECoG) induced by injections of thyrotropin-releasing hormone (TRH) into the left or right lateral brain ventricle in rats kept under conditions close to free behavior. It was found that these effects are characterized by a significant interhemisphere asymmetry. We postulate that the pharmacological (in particular, antidepressive) effects of TRH are related to its ability to intensify inhibitory processes in the left cerebral hemisphere and activating processes in the right hemisphere.
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收藏
页码：340 / 346
页数：7
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