Occurrence, biosynthesis, biological activity and NMR Spectroscopy of D and B, D ring seco-limonoids of Meliaceae family

被引:0
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作者
Narender, Tadigoppula [1 ]
Khaliq, Tanvir
Shweta
Reddy, Kancharla P.
Sharma, Ravi K.
机构
[1] Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India
[2] Cent Drug Res Inst, Documentat & Lib Div, Lucknow 226001, Uttar Pradesh, India
关键词
D-ring seco-limonoids; B; biosynthesis; biological activity; NMR spectroscopy; SWIETENIA-MAHAGONI JACQ; WEST-AFRICAN TIMBERS; PLATELET-ACTIVATING-FACTOR; CEDRELA ODORATA L; ANTIMALARIAL ACTIVITY; PHRAGMALIN LIMONOIDS; STEM BARK; KHAYA; TETRANORTRITERPENOIDS; EXTRACTIVES;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Limonoids are modified tetranortriterpenoids, classified on the basis of which of the four rings (A, B, C and D) in the intact triterpene nucleus have been oxidized. The order Rutales produces a variety of seco-limonoids, such as A, 13, C, D, AB, AD, and BD-ring seco-limonoids. The Meliaceae family, belonging to the order Rutales, has yielded several D-ring and B, D-ring seco-limonoids This review describes the occurrence, biosynthesis, biological activity and NMR spectroscopy of D ring seco-limonoids, such, as gedunin derivatives and B, D-ring seco-limonoids, such as methyl angolensates, xyloccensins, methyl meliacates, phragmalins and modified phragmalins. The literature from 1990 to 2005 is reviewed.
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页码:203 / 221
页数:19
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