Characterization and catalytic performance of Ni-Doped TiO2 as a potential heterogeneous nanocatalyst for the preparation of substituted pyridopyrimidines

被引：27

作者：

Kaiba, Abdellah ^{[1
]}

Ouerghi, Oussama ^{[1
,3
]}

Geesi, Mohammed H. ^{[2
]}

Elsanousi, Ammar ^{[1
]}

Belkacem, Afif ^{[1
]}

Dehbi, Oussama ^{[4
]}

Alharthi, Abdulrahman I. ^{[2
]}

Alotaibi, Mshari A. ^{[2
]}

Riadi, Yassine ^{[5
]}

机构：

[1] Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities Al Kharj, Dept Phys, Al Kharj 11942, Saudi Arabia

[2] Prince Sattam Bin Abdulaziz Univ, Coll Sci & Humanities, Dept Chem, Al Kharj 11942, Saudi Arabia

[3] Univ Tunis El Manar, Tunis 1068, Tunisia

[4] Aljaouf Univ, Coll Arts & Sci, Dept Chem, Al Qurayyat, Saudi Arabia

[5] Prince Sattam Bin Abdulaziz Univ, Coll Pharm, Dept Pharmaceut Chem, Al Kharj 11942, Saudi Arabia

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2020年 / 1203卷 / 1203期

关键词：

Ni-doped TiO2; Catalysis; Pyridopyrimidines; Heterogenous; TiO2; nanoparticles; REUSABLE CATALYST; COUPLING REACTION; NANOPARTICLES; EFFICIENT; DERIVATIVES; NANO-TIO2; PALLADIUM; ARYL; INHIBITORS; MECHANISM;

D O I：

10.1016/j.molstruc.2019.127376

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An effective and a novel synthesis route for accessing 2-substituted-pyridopyrimidines is described, starting from (2-amino-pyridin-3-yl)-methanol through the use of Ni-doped TiO2 nanoparticles as a heterogeneous catalyst. This approach involves the characterization and synthesis of Ni-doped TiO2 nanoparticles, followed by the optimization of the appropriate conditions for the reaction. This strategy affords an easy and efficient method to synthesize 2-substitued pyrido[2,3-d]pyrimidine compounds with an excellent yield (up to 92%). (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：5

共 59 条

[1] Diblydropyrido[2,3-d]pyrimidines as a new class of antfleishmanial agents [J].