Gastrointestinal complications of mitochondrial disease

被引：18
作者：
Hom, XB [1 ]
Lavine, JE
机构：
[1] Childrens Hosp, San Diego, CA USA
[2] Univ Calif San Diego, San Diego, CA 92130 USA
来源：
MITOCHONDRION | 2004年 / 4卷 / 5-6期
关键词：
mitochondrial disorders; dysphagia; feeding difficulties; gastrointestinal complications;
D O I：
10.1016/j.mito.2004.07.014
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The clinical presentation of mitochondrial disease can involve a number of organ systems which are seemingly unrelated. Gastrointestinal manifestations are often an early presentation of mitochondrial disorders. Dysphagia, feeding difficulties, gastroesophageal reflux, dysmotility with delayed gastric emptying, intestinal pseudo-obstruction, diarrhea and pancreatic exocrine insufficiency are amongst the major complications. Neuromuscular dysfunction affecting peristalsis is a common pathophysiologic mechanism causing many of these symptoms and treatment is primarily supportive. (C) 2004 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
引用
收藏
页码：601 / 607
页数：7
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