Radiotherapy for HCC: Ready for prime time?

被引：55

作者：

Bang, Andrew ^{[1
]}

Dawson, Laura A. ^{[1
]}

机构：

[1] Univ Toronto, Dept Radiat Oncol, Princess Margaret Canc Ctr, 610 Univ Ave, Toronto, ON M5G 2C1, Canada

来源：

JHEP REPORTS | 2019年 / 1卷 / 02期

关键词：

Stereotactic body radiation therapy; SBRT; Hepatocellular carcinoma; HCC; Protons; STEREOTACTIC BODY RADIOTHERAPY; UNRESECTABLE HEPATOCELLULAR-CARCINOMA; RADIATION-THERAPY; TRANSARTERIAL CHEMOEMBOLIZATION; RADIOFREQUENCY ABLATION; LIVER-TRANSPLANTATION; PHASE-I; CANCER; TOXICITY; TUMORS;

D O I：

10.1016/j.jhepr.2019.05.004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Stereotactic body radiation therapy (SBRT) has an evolving role in the management of hepatocellular carcinoma (HCC), largely due to recent advances in imaging technology. Often utilized in situations where other locoregional therapies are not feasible, SBRT has been demonstrated to be an effective treatment that confers high rates of durable local control. However, there is limited evidence to firmly establish its place in the treatment paradigm for HCC. In this article, we review the current evidence and highlight specific considerations in the multiple settings where SBRT may be used, including for primary HCC treatment and bridging/downstaging, as well as exploring the potential for SBRT in the treatment of extrahepatic oligo-metastatic HCC. (c) 2019 Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：131 / 137

页数：7

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