Cognitive Reserve in Dementia: Implications for Cognitive Training

被引：73

作者：

Mondini, Sara ^{[1
,2
,3
]}

Madella, Ileana ^{[1
]}

Zangrossi, Andrea ^{[1
,3
]}

Bigolin, Angela ^{[1
]}

Tomasi, Claudia ^{[1
,2
]}

Michieletto, Marta ^{[1
]}

Villani, Daniele ^{[2
]}

Di Giovanni, Giuseppina ^{[4
]}

Mapelli, Daniela ^{[1
,3
]}

机构：

[1] Univ Padua, Dept Gen Psychol, Padua, Italy

[2] Casa Cure Halle San Camillo, Neuromotor Rehabil Unit, Cremona, Italy

[3] Univ Padua, Human Inspired Technol Res Ctr, Padua, Italy

[4] IRCCS Ctr S Giovanni Dio Fatebenefratelli, Brescia, Italy

来源：

FRONTIERS IN AGING NEUROSCIENCE | 2016年 / 8卷

关键词：

cognitive reserve; dementia; Alzheimer's disease; cognitive training; rehabilitation; ALZHEIMERS-DISEASE; EDUCATION; PLASTICITY; RISK; INTERVENTION; ACTIVATIONS; STIMULATION; IMPAIRMENT; PREDICTORS; HEALTHY;

D O I：

10.3389/fnagi.2016.00084

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Cognitive reserve (CR) is a potential mechanism to cope with brain damage. The aim of this study was to evaluate the effect of CR on a cognitive training (CT) in a group of patients with dementia. Eighty six participants with mild to moderate dementia were identified by their level of CR quantified by the CR Index questionnaire (CRIq) and underwent a cycle of CT. A global measure of cognition mini mental state examination (MMSE) was obtained before (TO) and after (T1) the training. Multiple linear regression analyses highlighted CR as a significant factor able to predict changes in cognitive performance after the CT. In particular, patients with lower CR benefited from a CT program more than those with high CR. These data show that CR can modulate the outcome of a CT program and that it should be considered as a predictive factor of neuropsychological rehabilitation training efficacy in people with dementia.

引用

页数：7

共 53 条

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