Neonatal Acute Kidney Injury Understanding of the Impact on the Smallest Patients

被引:5
作者
Kavanaugh, Keegan J. [1 ]
Jetton, Jennifer G. [2 ]
Kent, Alison L. [3 ,4 ]
机构
[1] Univ Iowa, Stead Family Dept Pediat, 200 Hawkins Dr,2015-26 BT, Iowa City, IA 52241 USA
[2] Univ Iowa, Stead Family Dept Pediat, Div Pediat Nephrol Dialysis & Transplantat, 200 Hawkins Dr,2015-26 BT, Iowa City, IA 52241 USA
[3] Univ Rochester, Golisano Childrens Hosp, Sch Med, Div Neonatol, 601 Elmwood Ave,Box 651, Rochester, NY 14642 USA
[4] Australian Natl Univ, Coll Hlth & Med, Canberra, ACT 2601, Australia
关键词
Neonate; Acute kidney injury; Prematurity; Biomarkers; Outcomes;
D O I
10.1016/j.ccc.2020.11.007
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The study of neonatal acute kidney injury (AKI) has transitioned from small, single-center studies to the development of a large, multicenter cohort. The scope of research has expanded from assessment of incidence and mortality to analysis of more specific risk factors, novel urinary biomarkers, interplay between AKI and other organ systems, impact of fluid overload, and quality improvement efforts. The intensification has occurred through collaboration between the neonatology and nephrology communities. This review discusses 2 case scenarios to illustrate the clinical presentation of neonatal AKI, important risk factors, and approaches to minimize AKI events and adverse long-term outcomes. © 2020 Elsevier Inc.
引用
收藏
页码:349 / 363
页数:15
相关论文
共 69 条
[1]   Long-term follow-up of extremely low birth weight infants with neonatal renal failure [J].
Abitbol, CL ;
Bauer, CR ;
Montané, B ;
Chandar, J ;
Duara, S ;
Zilleruelo, G .
PEDIATRIC NEPHROLOGY, 2003, 18 (09) :887-893
[2]   Optimizing the AKI definition during first postnatal week using Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) cohort [J].
Askenazi, David ;
Abitbol, Carolyn ;
Boohaker, Louis ;
Griffin, Russell ;
Raina, Rupesh ;
Dower, Joshua ;
Davis, T. Keefe ;
Ray, Patricio E. ;
Perazzo, Sofia ;
DeFreitas, Marissa ;
Milner, Lawrence ;
Ambalavanan, Namasivayam ;
Cole, F. Sessions ;
Rademacher, Erin ;
Zappitelli, Michael ;
Mhanna, Maroun ;
Selewski, David T. ;
Sarkar, Subrata ;
Kent, Alison ;
Fletcher, Jeffery ;
Duara, Shahnaz ;
Charlton, Jennifer R. ;
Swanson, Jonathan R. ;
Guillet, Ronnie ;
D'Angio, Carl ;
Mian, Ayesa ;
Kumar, Deepak ;
Jetton, Jennifer G. ;
Brophy, Patrick D. ;
Colaizy, Tarah T. ;
Klein, Jonathan M. ;
Arikan, Ayse Akcan ;
Rhee, Christopher J. ;
Goldstein, Stuart L. ;
Nathan, Amy T. ;
Kupferman, Juan C. ;
Bhutada, Alok ;
Rastogi, Shantanu ;
Bonachea, Elizabeth ;
Mahan, John ;
Smith, Alexandra ;
Fuloria, Mamta ;
Reidy, Kimberly ;
Kaskel, Frederick J. ;
Soranno, Danielle E. ;
Gien, Jason ;
Gist, Katja M. ;
Chishti, Aftab S. ;
Hanna, Mina H. ;
Hingorani, Sangeeta .
PEDIATRIC RESEARCH, 2019, 85 (03) :329-338
[3]   Smaller circuits for smaller patients: improving renal support therapy with Aquadex™ [J].
Askenazi, David ;
Ingram, Daryl ;
White, Suzanne ;
Cramer, Monica ;
Borasino, Santiago ;
Coghill, Carl ;
Dill, Lynn ;
Tenney, Frank ;
Feig, Dan ;
Fathallah-Shaykh, Sahar .
PEDIATRIC NEPHROLOGY, 2016, 31 (05) :853-860
[4]   Acute Kidney Injury Urine Biomarkers in Very Low-Birth-Weight Infants [J].
Askenazi, David J. ;
Koralkar, Rajesh ;
Patil, Neha ;
Halloran, Brian ;
Ambalavanan, Namasivayam ;
Griffin, Russell .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2016, 11 (09) :1527-1535
[5]   Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate [J].
Askenazi, David J. ;
Koralkar, Rajesh ;
Hundley, Hayden E. ;
Montesanti, Angela ;
Patil, Neha ;
Ambalavanan, Namasivayam .
PEDIATRIC NEPHROLOGY, 2013, 28 (04) :661-666
[6]   Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case-control analysis [J].
Askenazi, David J. ;
Griffin, Russell ;
McGwin, Gerald ;
Carlo, Waldemar ;
Ambalavanan, Namasivayam .
PEDIATRIC NEPHROLOGY, 2009, 24 (05) :991-997
[7]   Acute kidney injury in critically ill newborns: What do we know? What do we need to learn? [J].
Askenazi, David J. ;
Ambalavanan, Namasivayam ;
Goldstein, Stuart L. .
PEDIATRIC NEPHROLOGY, 2009, 24 (02) :265-274
[8]   AWAKEN-Ing a New Frontier in Neonatal Nephrology [J].
Askenazi, David Joseph .
FRONTIERS IN PEDIATRICS, 2020, 8
[9]   Dynamic Biomarker Assessment: A Diagnostic Paradigm to Match the AKI Syndrome [J].
Basu, Rajit K. .
FRONTIERS IN PEDIATRICS, 2020, 7
[10]   Patent Ductus Arteriosus in Preterm Infants [J].
Benitz, William E. .
PEDIATRICS, 2016, 137 (01)