Natural killer cells in patients with Guillain-Barre syndrome

被引：18

作者：

Yoshii, F ^{[1
]}

Shinohara, Y

机构：

[1] Tokai Univ, Sch Med, Dept Neurol, Isehara, Kanagawa 2591193, Japan

[2] Hiratsuka City Hosp, Dept Neurol, Hiratsuka, Kanagawa 2540065, Japan

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1998年 / 157卷 / 02期

关键词：

natural killer cells; Guillain-Barre syndrome; natural killer cell activity; lymphocyte subsets; plasmapheresis;

D O I：

10.1016/S0022-510X(98)00065-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied natural killer (NK) cell activity and NK cell number in peripheral blood of 20 patients with Guillain-Barre syndrome (GBS). NK cell activity obtained within 7 days after onset of neuropathic symptoms in patients with GBS was significantly decreased compared with that in 20 control subjects. NK cell activity was not well correlated with disease severity. After plasmapheresis, NK cell activity recovered to the normal range. Two-color flow cytometry showed that the NK cell subsets studied were quantitatively similar in GBS patients and controls. (C) 1998 Elsevier Science B.V.

引用

页码：175 / 178

页数：4

共 16 条

[1] NK CELLS IN PATIENTS WITH PERIPHERAL NEUROPATHY AND IGM MONOCLONAL PROTEIN REACTING WITH THE MYELIN-ASSOCIATED GLYCOPROTEIN (MAG) [J].

ALBERIGHI, OD ;

ORAZIO, EN ;

BONARA, P ;

HU, C ;

SPAGNOL, G ;

RADELLI, L ;

SMERALDI, RS .

JOURNAL OF NEUROIMMUNOLOGY, 1988, 18 (03) :207-216

[2] HUMAN NATURAL-KILLER CLONES ENHANCE INVITRO ANTIBODY-PRODUCTION BY TUMOR-NECROSIS-FACTOR ALPHA-INTERFERON AND GAMMA-INTERFERON [J].

BECKER, JC ;

KOLANUS, W ;

LONNEMANN, C ;

SCHMIDT, RE .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1990, 32 (02) :153-162

[3] T-LYMPHOCYTE SUBSET ABNORMALITIES IN PERIPHERAL-BLOOD FROM PATIENTS WITH THE GUILLAIN-BARRE-SYNDROME [J].

DAHLE, C ;

VRETHEM, M ;

ERNERUDH, J .

JOURNAL OF NEUROIMMUNOLOGY, 1994, 53 (02) :219-225

[4] NATURAL-KILLER (NK) CELLS IN CHRONIC PROGRESSIVE MULTIPLE-SCLEROSIS PATIENTS TREATED WITH LYMPHOBLASTOID INTERFERON [J].

KASTRUKOFF, LF ;

MORGAN, NG ;

AZIZ, TM ;

ZECCHINI, D ;

BERKOWITZ, J ;

PATY, DW .

JOURNAL OF NEUROIMMUNOLOGY, 1988, 20 (01) :15-23

[5]

KUWANO K, 1986, J IMMUNOL, V137, P1462

[6]

MICHAEL A, 1989, J IMMUNOL, V142, P1095

[7]

MURRAY N, 1984, LANCET, V2, P711

[8]

NEIGHBOUR PA, 1982, CLIN EXP IMMUNOL, V49, P11

[9] MODULATION OF NATURAL-KILLER CELL-ACTIVITY IN PERIPHERAL-BLOOD BY PHYSICAL EXERCISE [J].

PEDERSEN, BK ;

TVEDE, N ;

HANSEN, FR ;

ANDERSEN, V ;

BENDIX, T ;

BENDIXEN, G ;

BENDTZEN, K ;

GALBO, H ;

HAAHR, PM ;

KLARLUND, K ;

SYLVEST, J ;

THOMSEN, BS ;

HALKJAERKRISTENSEN, J .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1988, 27 (06) :673-678

[10] A SHARED ANTIGENIC DETERMINANT BETWEEN NATURAL-KILLER CELLS AND NERVOUS-TISSUE [J].

SCHULLERPETROVIC, S ;

GEBHART, W ;

LASSMANN, H ;

RUMPOLD, H ;

KRAFT, D .

NATURE, 1983, 306 (5939) :179-181

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