Iron transporter DMT1 regulates endosome-mitochondria dynamics, mitochondrial metabolism and invasive migration in breast cancer cells

被引：0
|
作者：
Barra, Jonathan
Nelson, Iram
Elder, Lauren
Wang, Ling
Barroso, Margarida
机构：
来源：
FASEB JOURNAL | 2021年 / 35卷
关键词：
D O I：
10.1096/fasebj.2021.35.S1.03328
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Mitochondria "fuel" breast cancer metabolism Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
    Sotgia, Federica
    Whitaker-Menezes, Diana
    Martinez-Outschoorn, Ubaldo E.
    Salem, Ahmed F.
    Tsirigos, Aristotelis
    Lamb, Rebecca
    Sneddon, Sharon
    Hulit, James
    Howell, Anthony
    Lisanti, Michael P.
    CELL CYCLE, 2012, 11 (23) : 4390 - 4401
  • [42] Mitochondrial Dynamics Protein Drp1 Is Overexpressed in Oncocytic Thyroid Tumors and Regulates Cancer Cell Migration
    Ferreira-da-Silva, Andre
    Valacca, Cristina
    Rios, Elisabete
    Populo, Helena
    Soares, Paula
    Sobrinho-Simoes, Manuel
    Scorrano, Luca
    Maximo, Valdemar
    Campello, Silvia
    PLOS ONE, 2015, 10 (03):
  • [43] A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms
    Vayalil, Praveen K.
    Oh, Joo-Yeun
    Zhou, Fen
    Diers, Anne R.
    Smith, M. Ryan
    Golzarian, Hafez
    Oliver, Patsy G.
    Smith, Robin A. J.
    Murphy, Michael P.
    Velu, Sadanandan E.
    Landar, Aimee
    PLOS ONE, 2015, 10 (03):
  • [44] Protein kinase Cα regulates Ets1 transcriptional activity in invasive breast cancer cells
    Lindemann, RK
    Braig, M
    Ballschmieter, P
    Guise, TA
    Nordheim, A
    Dittmer, J
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2003, 22 (04) : 799 - 805
  • [45] Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells
    Gan, Delu
    Yue, Shujun
    Jiang, Yulin
    Zhang, Dian
    Shi, He
    Qian, Husun
    Zhou, Ting
    Fang, Wenli
    Yao, Mengli
    Zuo, Guowei
    Chen, Tingmei
    LIFE SCIENCES, 2020, 253
  • [46] Deferoxamine-induced high expression of TfR1 and DMT1 enhanced iron uptake in triple-negative breast cancer cells by activating IL-6/PI3K/AKT pathway
    Chen, Chunli
    Liu, Ping
    Duan, Xiaoyue
    Cheng, Man
    Xu, Lisa X.
    ONCOTARGETS AND THERAPY, 2019, 12 : 4359 - 4377
  • [47] MCT1 Expression in Breast Cancer: Evidence of Increased Mitochondrial Metabolism in Triple Negative Invasive Ductal Carcinomas
    Cotzia, Paolo
    Colombo, Daniele
    Bombonati, Alessandro
    Birbe, Ruth
    O'Neill, Raymond
    Draganova-Tacheva, Rossitza
    Tuluc, Madalina
    Mollaee, Mehri
    Palazzo, Juan
    Martinez-Outschoorn, Ubaldo
    LABORATORY INVESTIGATION, 2015, 95 : 39A - 39A
  • [48] MCT1 Expression in Breast Cancer: Evidence of Increased Mitochondrial Metabolism in Triple Negative Invasive Ductal Carcinomas
    Cotzia, Paolo
    Colombo, Daniele
    Bombonati, Alessandro
    Birbe, Ruth
    O'Neill, Raymond
    Draganova-Tacheva, Rossitza
    Tuluc, Madalina
    Mollaee, Mehri
    Palazzo, Juan
    Martinez-Outschoorn, Ubaldo
    MODERN PATHOLOGY, 2015, 28 : 39A - 39A
  • [49] MED28 regulates MEK1-dependent cellular migration in human breast cancer cells
    Huang, Chun-Yin
    Chou, Yu-Hsuan
    Hsieh, Nien-Tsu
    Chen, Hsin-Hung
    Lee, Ming-Fen
    JOURNAL OF CELLULAR PHYSIOLOGY, 2012, 227 (12) : 3820 - 3827
  • [50] Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties
    Yu, Yang
    Wu, Xiao'an
    Liu, Sisi
    Zhao, Hongping
    Li, Bo
    Zhao, Hucheng
    Feng, Xiqiao
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 53 (01) : 10 - 18
12345