Dosimetric characteristics of a reusable 3D radiochromic dosimetry material

被引:4
|
作者
Park, Jong Min [1 ,2 ,3 ,4 ]
Park, So-Yeon [1 ,2 ,3 ]
Choi, Chang Heon [1 ,2 ,3 ]
Chun, Minsoo [1 ,2 ,3 ]
Han, Ji Hye [1 ,3 ]
Cho, Jin Dong [1 ,3 ]
Kim, Jung-in [1 ,2 ,3 ]
机构
[1] Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul, South Korea
[2] Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, Seoul, South Korea
[3] Seoul Natl Univ Hosp, Biomed Res Inst, Seoul, South Korea
[4] Adv Inst Convergence Technol, Ctr Convergence Res Robot, Suwon, South Korea
来源
PLOS ONE | 2017年 / 12卷 / 07期
基金
新加坡国家研究基金会;
关键词
IMRT; RADIATION; THERAPY; BEAM; VMAT;
D O I
10.1371/journal.pone.0180970
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Purpose To investigate the dosimetric characteristics of PRESAGE(REU) dosimeters. Methods Commercially available PRESAGE REU dosimeters (size of 10 mm x 10 mm x 45 mm) were divided into two groups, with one of the groups placed at room temperature of 22 degrees C (RT group) and another group placed at low temperature of 10 E C (LT group). A total of 3 dosimeters (set of dosimeters) were irradiated at a time, with doses of 1 Gy, 2 Gy, 4 Gy, 8 Gy, 12 Gy, 16 Gy, and 20 Gy, at a nominal dose rate of 400 MU/min at temperature of 22 degrees C. The dosimeters were irradiated three additional times by delivering the same doses as those during the initial irradiations (4 irradiation cycles). Optical density (OD) was assessed using optical CT scanning. Results Considering both linearity and sensitivity of the OD curves, R-2 above 0.95 and sensitivity above 0.04 Delta OD/Gy were observed at the 1 st irradiation (reading time <= 6 h) and 2 nd irradiation (reading time = 0.5 h) for the RT group. For the LT group, those values were observed at the 1 st irradiation (reading time <= 2 h), and the 3 rd and 4 th irradiations (both reading times = 0.5 h). Considering the reproducibility of signals in response to the same dose, dosimeters in the RT group showed average deviations among dosimeters less than 5% (the 1 st and 2 nd irradiations at the reading time of 0.5 h), while for dosimeters in the LT group showed average deviations among dosimeters less than 6% (the 3 rd and 4 th irradiations at the reading time of 0.5 h). For the rest, the OD curves were not linear, sensitivities of the dosimeters were lower than 0.04.OD/Gy, and OD deviations at the same dose were larger than 6%. Conclusions At room temperature, PRESAGE(REU) dosimeters could be used for dose measurement only for up to two dose measurement sessions. At low temperatures, usage of PRESAGE(REU) dosimeters for dose measurement seems to be possible from the 3 rd irradiation. When reusing PRESAGE REU dosimeters, the OD curve should be re-defined for every measurement session because the shape of this curve depends on the irradiation history.
引用
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页数:16
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