Phytochemical Analysis and Study of Antioxidant, Anticandidal, and Antibacterial Activities of Teucrium polium subsp. polium and Micromeria graeca (Lamiaceae) Essential Oils from Northern Morocco

被引：13

作者：

Benali, Taoufiq ^{[1
,2
]}

Habbadi, Khaoula ^{[3
]}

Bouyahya, Abdelhakim ^{[4
,5
]}

Khabbach, Abdelmajid ^{[6
]}

Marmouzi, Ilias ^{[7
]}

Aanniz, Tarik ^{[8
]}

Chtibi, Houda ^{[2
]}

Mrabti, Hanae Naceiri ^{[9
]}

Achbani, El Hassan ^{[3
]}

Hammani, Khalil ^{[2
]}

机构：

[1] Cadi Ayyad Univ, Polydisciplinary Fac Safi, Environm & Hlth Team, Marrakech, Morocco

[2] Sidi Mohamed Ben Abdellah Univ, Polydisciplinary Fac Taza, Lab Nat Resources & Environm, BP 1223, Taza Gare, Taza, Morocco

[3] Lab Rech & Protect Plantes URPP INRA Meknes, Meknes, Morocco

[4] Mohammed V Univ Rabat, Lab Human Pathol Biol, Dept Biol, Fac Sci, Rabat, Morocco

[5] Mohammed V Univ Rabat, Genom Ctr Human Pathol, Fac Med & Pharm, Rabat, Morocco

[6] Sidi Mohamed Ben Abdellah Univ, Polydisciplinary Fac Taza, Lab Mat Nat Subst Environm & Modeling, BP 1223, Taza Gare, Taza, Morocco

[7] Univ Mohammed V Rabat, Fac Med & Pharm, Rabat Inst, Lab Pharmacol & Toxicol, BP 6203, Rabat, Morocco

[8] Mohammed V Univ Rabat, Rabat Med & Pharm Sch, Med Biotechnol Lab MedBiotech, Rabat 6203, Morocco

[9] Mohammed V Univ Rabat, Fac Med & Pharm, Lab Pharmacol & Toxicol, Bio Pharmaceut & Toxicol Anal Res Team, BP 6203, Rabat, Morocco

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2021年 / 2021卷

关键词：

VITRO ANTIMICROBIAL ACTIVITY; PLANT ESSENTIAL OILS; OCIMUM-BASILICUM L; CHEMICAL-COMPOSITION; ROSMARINUS-OFFICINALIS; EUCALYPTUS-GLOBULUS; ANTICANCER ACTIVITY; ALPHA-PINENE; INSECTICIDAL ACTIVITY; MEDICINAL-PLANTS;

D O I：

10.1155/2021/6641720

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

The protection of agricultural crops and the preservation of the organoleptic and health qualities of food products represent a major challenge for the agricultural and agro-food industries. Essential oils have received greater attention as alternatives to replace the control strategies based on pesticides against phytopathogenic bacteria and synthetic compounds in food preservation. The aims of this work were to study the chemical composition of Teucrium polium subsp. polium and Micromeria graeca essential oils and to examine their antioxidant and antimicrobial effects. To carry out this work, the chemical composition of the essential oil was determined using gas chromatography (GC) with the detection feature of mass spectrometry (MS). Subsequently, the antioxidant activity was investigated by DPPH and FRAPS assays. The antimicrobial effect was studied against phytopathogenic and foodborne pathogenic bacteria using the disc and the microdilution methods. Our results showed that GC-MS analysis of EOs allowed the identification of 30 compounds in T. polium EO (TPpEO), while 5 compounds were identified in M. graeca EO (MGEO). TPpEO had as major compounds beta-pinene (19.82%) and germacrene D (18.33%), while geranial (36.93%) and z-citral (18.25%) were the main components of MGEO. The most potent activity was obtained from MGEO (IC50 = 189.7 +/- 2.62 mu g/mL) compared to TPpEO (IC50 = 208.33 +/- 3.51 mu g/mL. For the FRAP test, the highest reducing power was obtained from 1.32 +/- 0.1 mg AAE/g of TPpEO compared to MGEO 0.51 +/- 0.13 mg AAE/g of EO. Both EOs exhibited varying degrees of antibacterial activities against all the tested strains with inhibition zones in the range of 9.33 +/- 0.57 mm to >65 mm and MIC values from 0.19 to 12.5 mg/mL. However, MGEO exhibits an interesting anticandidal effect with inhibition zone 44.33 +/- 0.57 mm. The findings of this research establish the riches of EOs on volatile compounds, their important antioxidant activity, and their antimicrobial effect against the bacteria tested.

引用

页数：10

共 99 条

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