The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions

被引：346

作者：

Nedergaard, Jan ^{[1
]}

Cannon, Barbara ^{[1
]}

机构：

[1] Stockholm Univ, Wenner Gren Inst, Arrhenius Labs, SE-10691 Stockholm, Sweden

来源：

CELL METABOLISM | 2010年 / 11卷 / 04期

基金：

瑞典研究理事会;

关键词：

THERMOGENESIS; ADIPOCYTES; MICE; UCP1;

D O I：

10.1016/j.cmet.2010.03.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

That adult humans possess active brown adipose tissue potentially leads to a paradigm shift in the understanding of human metabolism and of obesity. Adaptive adrenergic thermogenesis in humans represents brown adipose tissue activity, the absence of which may contribute to middle-age obesity.

引用

页码：268 / 272

页数：5

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