Enzymatic synthesis of a catechin conjugate of polyhedral oligomeric silsesquioxane and evaluation of its antioxidant activity

被引：25

作者：

Ihara, N ^{[1
]}

Kurisawa, M ^{[1
]}

Chung, JE ^{[1
]}

Uyama, H ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6158510, Japan

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2005年 / 66卷 / 04期

关键词：

D O I：

10.1007/s00253-004-1653-z

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The antioxidant activity of catechin was amplified by conjugation with amine-terminated polyhedral oligomeric silsesquioxane (POSS) using horseradish peroxidase as catalyst. Compared to intact catechin, the scavenging activity of the POSS-catechin conjugate against superoxide anion was greatly improved. In addition, the conjugate strongly inhibited xanthine oxidase activity.

引用

页码：430 / 433

页数：4

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