More kapakahines from the marine sponge cribrochalina Olemda

被引：72

作者：

Nakao, Y

Kuo, J

Yoshida, WY

Kelly, M

Scheuer, PJ

机构：

[1] Harbor Branch Oceanog Inst Inc, Ft Pierce, FL 34936 USA

[2] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 09期

关键词：

D O I：

10.1021/ol026830u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

graphic Three new kapakahines E-G (1-3) have been isolated from the marine sponge Cribrochalina olemda. Limited quantities of these compounds required not only NMR analysis but also FAB-MS/MS analysis for the structure elucidation. Kapakahine E showed cytotoxicity against P388 murine leukemia cells.

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页码：1387 / 1390

页数：4

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