pH- and thermosensitive supramolecular assembling system:: Rapidly responsive properties of β-cyclodextrin-conjugated poly(ε-lysine)

被引:101
作者
Choi, HS [1 ]
Huh, KM [1 ]
Ooya, T [1 ]
Yui, N [1 ]
机构
[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Tatsunokuchi, Ishikawa 9231292, Japan
关键词
D O I
10.1021/ja034149x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
β-Cyclodextrin-conjugated poly(ε-lysine) (β-CDPL) was synthesized as a novel polymeric host for constructing a smart supramolecular assembling system. Systematic studies on the inclusion complexation between the polymeric host with an α- or β-CD cavity and a model guest molecule provided evidence that dual cooperative interactions, specific host-guest interaction and intermolecular ionic interaction, played a dominant role in leading to a fast aggregation phenomenon. In addition, a rapid phase transition induced by the supramolecular assembly was observed reversibly in response to a small change in pH or temperature. Copyright © 2003 American Chemical Society.
引用
收藏
页码:6350 / 6351
页数:2
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