The functioning assessment short test (FAST) applied to first-episode psychosis: Psychometric properties and severity thresholds

被引:23
作者
Amoretti, Silvia [1 ,2 ,3 ,4 ]
Mezquida, Gisela [1 ,2 ,3 ]
Rosa, Adriane R. [4 ,5 ,6 ,7 ]
Bioque, Miquel [1 ,2 ,3 ]
Cuesta, Manuel J. [4 ,8 ,9 ]
Pina-Camacho, Laura [3 ,10 ]
Garcia-Rizo, Clemente [1 ,2 ,3 ,4 ]
Barcones, Fe [11 ,12 ]
Gonzalez-Pinto, Ana [3 ,13 ]
Merchan-Naranjo, Jessica [3 ]
Corripio, Iluminada [3 ,14 ]
Vieta, Eduard [2 ,3 ,4 ,15 ]
Baeza, Inmaculada [2 ,3 ,4 ,16 ]
Cortizo, Romina [2 ,17 ]
Bonnin, C. Mar [2 ,3 ,4 ]
Torrent, Carla [2 ,3 ,4 ]
Bernardo, Miguel [1 ,2 ,3 ,4 ]
机构
[1] Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
[2] Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
[3] Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
[4] August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
[5] Hosp Clin Porto Alegre, Lab Mol Psychiat, Porto Alegre, RS, Brazil
[6] Univ Fed Rio Grande UFRGS, Dept Pharmacol, Porto Alegre, RS, Brazil
[7] Univ Fed Rio Grande UFRGS, Postgrad Program Psychiat & Behav Sci, Porto Alegre, RS, Brazil
[8] Complejo Hosp Navarra, Dept Psychiat, Pamplona, Spain
[9] Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain
[10] Univ Complutense, Dept Child & Adolescent Psychiat, Inst Psychatry & Mental Hlth, Hosp Gen Univ Gregorio Maranon,IiSGM,Sch Med, Madrid, Spain
[11] Hosp Univ Miguel Servet, Dept Family Med, Zaragoza, Spain
[12] Univ Zaragoza, Dept Med & Psychiat, Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain
[13] Univ Basque Country, Bioaraba Res Inst, Dept Neuroci, Dept Psychiat,Araba Univ Hosp, Vitoria, Spain
[14] Univ Autonoma Barcelona UAB, Hosp Santa Creu & St Pau, Dept Psychiat, Inst Invest Biomed St Pau IIBSANT PAU, Barcelona, Spain
[15] Hosp Clin Barcelona, Neurosci Inst, Bipolar & Depress Disorders Unit, Barcelona, Spain
[16] Univ Barcelona, Hosp Clin Barcelona, Dept Child & Adolescent Psychiat & Psychol, Clin Inst Neurosci, 2017SGR881, Barcelona, Spain
[17] Inst Neuropsiquiatria Adicciones INAD, Barcelona, Spain
关键词
First episode; Schizophrenia; Psychometrics; Early intervention; SCHIZOPHRENIA SPECTRUM DISORDERS; COGNITIVE RESERVE; BIPOLAR DISORDER; 1ST EPISODE; RECOVERY; VALIDITY; OUTCOMES; RELIABILITY; PREDICTORS; DEPRESSION;
D O I
10.1016/j.euroneuro.2021.02.007
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Functional impairment is a defining feature of psychotic disorders. The Functional Assessment Short Test (FAST) is one of the most widely used instruments to measure psychosocial functioning. However, cut-offs of impairment have been well-established for bipolar disorders, but not for other clinical populations. This study aims to analyse psychometric properties of the FAST and establish their corresponding cut-off values for the different severity gradations in a first-episode of non-affective psychosis (FEP) patients. Global Assessment Functioning (GAF) and FAST ratings from 212 non-affective FEP and 204 healthy controls were analyzed. The psychometric properties of FAST (internal consistency, concurrent validity, discriminant validity, factorial analyses and sensitivity to change) were analyzed. The severity gradations of the FAST were defined by the congruence between two grading methods: linear regression analysis (LRA) and percentiles. The FAST showed strong psychometric properties. LRA with the GAF scores yielded the following equation: GAF(score) = 80.83 - 0.639*FAST(score). The FAST ranges in non-affective FEP patients derived from LRA and percentiles, were as follows: 0-9 (No impairment); 10-19 (Minimal impairment); 20-34 (Mild impairment); 35-45 (Moderate impairment); 46-72 (Severe impairment). Patients with no functional impairment had a higher socioeconomic status, fewer depressive and negative symptoms, lower severity of illness and higher cognitive reserve level than the others groups. In conclusion, the FAST shows optimal psychometric properties which corroborate its applicability in FEP populations. It is a well-demonstrated valid instrument and the present cut-off scores could be implemented in clinical and research practice to assess properly the psychosocial functional outcome of non-affective FEP populations. (C) 2021 Elsevier B.V. and ECNP. All rights reserved.
引用
收藏
页码:98 / 111
页数:14
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