Ruthenium(II)-Catalyzed Oxidative Double C-H Activation and Annulation Reaction: Synthesis of Indolo[2,1-a]isoquinolines

被引：36

作者：

Borthakur, Somadrita ^{[1
]}

Sarma, Bipul ^{[2
]}

Gogoi, Sanjib ^{[1
]}

机构：

[1] AcSIR, Appl Organ Chem Chem Sci & Technol Div, CSIR North East Inst Sci & Technol, Jorhat 785006, Assam, India

[2] Tezpur Univ, Dept Chem Sci, Tezpur 784028, India

来源：

ORGANIC LETTERS | 2019年 / 21卷 / 19期

关键词：

RECEPTOR-BINDING AFFINITIES; ALKYNES; MULTIPLE; CLEAVAGE; INDOLES;

D O I：

10.1021/acs.orglett.9b02871

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first metal-catalyzed double aryl C(sp(2))-H bond activation of antipyrine and alkyne annulation reaction is reported. This Ru(II)-catalyzed reaction was accomplished in the presence of 20 mol % phosphine ligand tricyclohexylphosphine tetrafluoroborate to afford indolo[2,1-a]isoquinolines that are very important compounds because of their bioactivity and interesting optical properties.

引用

页码：7878 / 7882

页数：5

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