Catalytic asymmetric synthesis and optical resolution of planar chiral rotaxane

被引：55

作者：

Makita, Yoshimasa

Kihara, Nobuhiro

Nakakoji, Naohisa

Takata, Toshikazu ^{[1
]}

Inagaki, Shinji

Yamamoto, Chiyo

Okamoto, Yoshio

机构：

[1] Tokyo Inst Technol, Dept Organ & Polymer Mat, Meguro Ku, Tokyo 1528552, Japan

[2] Kanagawa Univ, Fac Sci, Dept Chem, Hiratsuka, Kanagawa 2591293, Japan

[3] Osaka Prefecture Univ, Grad Sch Engn, Dept Appl Chem, Sakai, Osaka 5998531, Japan

[4] Nagoya Univ, Grad Sch Engn, Dept Appl Chem, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

CHEMISTRY LETTERS | 2007年 / 36卷 / 01期

关键词：

D O I：

10.1246/cl.2007.162

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Planar chiral rotaxanes were synthesized from crown ether and secondary ammonium salt via trialkylphosphane-catalyzed acylative end-capping. Their optical resolution was achieved by chiral HPLC after acylative neutralization of the ammonium group. When optically active trialkylphosphane 2 was used as the chiral acylation catalyst, optically active rotaxane (4.4% ee) was obtained.

引用

页码：162 / 163

页数：2

共 43 条

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