Infectious mononucleosis and multiple sclerosis - Updated review on associated risk

被引：24

作者：

Sheik-Ali, Sharaf ^{[1
]}

机构：

[1] Barts & London Queen Marys Sch Med & Dent, London, England

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2017年 / 14卷

关键词：

Infections; MS; Multiple Sclerosis;

D O I：

10.1016/j.msard.2017.02.019

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: There has been substantial evidence accumulating on the role of infectious mononucleosis (IM) and the subsequent risk of obtaining Multiple Sclerosis (MS). Up to date studies not previously explored were reviewed by the author to further clarify the association. Methods: Medline and Web of Science were searched with no time constraints for articles exploring an association between Multiple Sclerosis and Infectious Mononucleosis. 24 articles were found, totalling 1063 cases and 13,227 cohort/controls. Results: 23/24 (96%) articles reported a significant association of Infectious Mononucleosis on the risk of subsequent multiple sclerosis. Discussion: Overall, new literature on IM and risk of MS categorically supports the association. Future work should focus on other risk factors such as age and gender on TM and subsequent risk of MS.

引用

页码：56 / 59

页数：4