Separation Characteristics of Crystalline Amino Acids with Regard to the Modularization Idea

被引:9
作者
Loebnitz, Lisa [1 ]
Singer, Jan [1 ]
Anlauf, Harald [1 ]
Nirschl, Hermann [1 ]
机构
[1] Karlsruhe Inst Technol, Inst Mech Proc Engn & Mech, Str Forum 8, D-76131 Karlsruhe, Germany
关键词
Amino acids; Crystallization; Modularization; Solid-liquid separation; ACTIVE PHARMACEUTICAL INGREDIENTS; GLUTAMIC-ACID; SMALL-SCALE; PLANT; PURIFICATION; PERSPECTIVE; FILTRATION; DESIGN;
D O I
10.1002/ceat.201600527
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
In the chemical and pharmaceutical industry, a fast and efficient market launch is important to withstand global competition. Apart from the innovation of new products, the development of an appropriate production line is time-consuming. Modularization can accelerate the design and commissioning of a production plant. Herein, representative of a pharmaceutical process, the production, precisely the solid-liquid separation, of amino acids is considered. Therefore, the separation behavior of different amino acid systems and variations within solid systems are examined. With this information, a production plant is designed and differences regarding the amino acid systems are identified.
引用
收藏
页码:1577 / 1583
页数:7
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