Hyperglycemia aggravates acute liver injury by promoting macrophage NLRP3 activation via AMPK/mTOR-dependent autophagy inhibition

被引：0
|
作者：
Zhou, H. [1 ]
Wang, Q. [1 ]
Liu, R. [1 ]
Zhou, S. [1 ]
Shi, C. [1 ]
Wei, S. [1 ]
Rao, Z. [1 ]
Cheng, F. [1 ]
Wang, X. [1 ]
Lyu, L. [1 ]
机构：
[1] Nanjing Med Univ, Affiliated Hosp 1, Liver Transplant Ctr, Nanjing, Jiangsu, Peoples R China
来源：
TRANSPLANTATION | 2019年 / 103卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
P-348
引用
收藏
页码：267 / 268
页数：2
相关论文
共 50 条
  • [1] Hyperglycemia Aggravates Acute Liver Injury by Promoting Macrophage NLRP3 Activation via AMPK/mTOR-Dependent Autophagy Inhibition.
    Zhou, H.
    Wang, Q.
    Liu, R.
    Zhou, S.
    Cheng, F.
    Wang, X.
    Lu, L.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2019, 19 : 896 - 897
  • [2] Hyperglycemia aggravates acute liver injury by promoting liver-resident macrophage NLRP3 inflammasome activation via the inhibition of AMPK/mTOR-mediated autophagy induction
    Wang, Qi
    Wei, Song
    Zhou, Shun
    Qiu, Jiannan
    Shi, Chenyu
    Liu, Rui
    Zhou, Haoming
    Lu, Ling
    IMMUNOLOGY AND CELL BIOLOGY, 2020, 98 (01): : 54 - 66
  • [3] HYPERGLYCEMIA AGGRAVATES ACUTE LIVER INJURY BY PROMOTING LIVER-RESIDENT MACROPHAGE NLRP3 INFLAMMASOME ACTIVATION VIA THE INHIBITION OF AMPK/MTOR-MEDIATED AUTOPHAGY INDUCTION
    Wang Qi
    Wei Song
    Zhou Haoming
    Lu Ling
    TRANSPLANTATION, 2020, 104 (09) : S526 - S526
  • [4] Hyperglycemia aggravates acute liver injury by promoting liver-resident macrophage NLRP3 inflammasome activation via inhibiting AMPK/mTOR-mediated autophagy induction
    Wang, Q.
    Wei, S.
    Zhou, S.
    Zhou, H.
    Lu, L.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 216 - 216
  • [5] Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy
    Yang, Fan
    Qin, Ying
    Wang, Yueqiu
    Meng, Songyan
    Xian, Huimin
    Che, Hui
    Lv, Jie
    Li, Yang
    Yu, Yahan
    Bai, Yunlong
    Wang, Lihong
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019, 15 (05): : 1010 - 1019
  • [6] Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice
    Han, Jihye
    Bae, Joonbeom
    Choi, Chang-Yong
    Choi, Sang-Pil
    Kang, Hyung-Sik
    Jo, Eun-Kyeong
    Park, Jongsun
    Lee, Young Sik
    Moon, Hyun-Seuk
    Park, Chung-Gyu
    Lee, Myung-Shik
    Chun, Taehoon
    AUTOPHAGY, 2016, 12 (12) : 2326 - 2343
  • [7] Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway
    Cui, Lihua
    Li, Caixia
    Zhuo, Yuzhen
    Yang, Lei
    Cui, Naiqiang
    Li, Yuhong
    Zhang, Shukun
    BIOMEDICINE & PHARMACOTHERAPY, 2020, 128
  • [8] Stefin B Inhibits NLRP3 Inflammasome Activation via AMPK/mTOR Signalling
    Trstenjak-Prebanda, Mojca
    Biasizzo, Monika
    Dolinar, Klemen
    Pirkmajer, Sergej
    Turk, Boris
    Brault, Veronique
    Herault, Yann
    Kopitar-Jerala, Natasa
    CELLS, 2023, 12 (23)
  • [9] Estrogen receptor α aggravates intestinal inflammation via promoting the activation of NLRP3 inflammasome
    Gao, Zhangshan
    Ding, Chenchen
    Huang, Xi
    Liu, Yapei
    Fan, Wentao
    Song, Suquan
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 143
  • [10] HYPOXIA AMELIORATES INFLAMMATION THROUGH THE INHIBITION OF NLRP3/MTOR SIGNALING AND THE ACTIVATION OF AUTOPHAGY
    Cosin-Roger, Jesus
    Simmen, Simona
    Melhem, Hassan
    Atrott, Kirstin
    Frey-Wagner, Isabelle
    Hausmann, Martin
    de Valliere, Cheryl
    Spalinger, Marianne
    Patrick, S.
    Wenger, Roland H.
    Zeitz, Jonas
    Vavricka, Stephan R.
    Rogler, Gerhard
    Ruiz, Pedro
    GASTROENTEROLOGY, 2017, 152 (05) : S739 - S739
12345