Clinical Features and Cutaneous Manifestations of Juvenile and Adult Patients of Dermatomyositis Associated with Myositis-Specific Autoantibodies

被引：11

作者：

Okiyama, Naoko ^{[1
]}

机构：

[1] Univ Tsukuba, Fac Med, Dept Dermatol, Ibaraki 3058575, Japan

来源：

JOURNAL OF CLINICAL MEDICINE | 2021年 / 10卷 / 08期

关键词：

dermatomyositis; skin; autoantibody;

D O I：

10.3390/jcm10081725

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dermatomyositis is one of the idiopathic inflammatory myopathies, which is characterized with specific skin manifestations, and considered as an autoimmune disease. Dermatomyositis is a heterogeneous disorder with various presences, severities and characteristics of myositis, dermatitis, and interstitial lung disease. Our and others' data showed that myositis-specific autoantibodies have been associated with distinct clinical features. This article reviewed the epidemiology and characteristic clinical features of the different types of antibody-associated dermatomyositis in adult and juvenile patients, which include the severity of myopathy, the potential complication of interstitial lung disease, potential association with malignancies, and characteristic cutaneous manifestations.

引用

页数：7

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