Ytterbium triflate catalyzed synthesis of β-enaminones

被引：91
作者：
Epifano, Francesco
Genovese, Salvatore
Curini, Massimo
机构：
[1] Dipartimento Sci Farmaco, I-66013 Chieti, Italy
[2] Sez Chim Organ, Dipartimento Chim & Tecnol Farmaco, I-06123 Perugia, Italy
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 15期
关键词：
amine; beta-enaminone; beta-dicarbonyl compounds; heterogeneous catalysis; ytterbium triflate;
D O I：
10.1016/j.tetlet.2007.02.064
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
beta-Enaminones have been synthesized in very good yield under solvent-free conditions from differently substituted amines and beta-diketones in the presence of Yb(OTf)(3) as catalyst. The method is applicable to cyclic and acyclic ketones, aromatic and aliphatic amines without differences. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2717 / 2720
页数：4
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