Management of Gastropathy and Gastric Vascular Ectasia in Portal Hypertension

被引:44
作者
Ripoll, Cristina [3 ]
Garcia-Tsao, Guadalupe [1 ,2 ]
机构
[1] Yale Univ, Sch Med, Sect Digest Dis, New Haven, CT 06510 USA
[2] VA CT Healthcare Syst, New Haven, CT 06510 USA
[3] Hosp Gen Univ Gregorio Maranon, Area 6300, Dept Digest Dis, Hepatol & Liver Transplant Unit, Madrid, Spain
关键词
Portal hypertensive gastropathy; Gastric antral vascular ectasia; Portal hypertension; Cirrhosis; Management; ARGON PLASMA COAGULATION; INTRAHEPATIC PORTOSYSTEMIC SHUNT; VENOUS-PRESSURE GRADIENT; WATERMELON STOMACH; CIRRHOTIC-PATIENTS; NATURAL-HISTORY; CAPSULE ENDOSCOPY; GI TRACT; LESIONS; GAVE;
D O I
10.1016/j.cld.2010.03.013
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Portal hypertensive gastropathy and gastric antral vascular ectasia may cause gastrointestinal hemorrhage in patients with portal hypertension. Whereas the former presents exclusively in patients with portal hypertension, gastric antral vascular ectasia can also be observed in patients with other conditions. Diagnosis is established with upper gastrointestinal endoscopy, although some cases may require a biopsy to confirm the diagnosis. The most frequent manifestation is ferropenic anemia, which may become transfusion dependent. Treatment in portal hypertensive gastropathy is focused on portal pressure reducing drugs, mainly nonselective beta-blockers, whereas in gastric antral vascular ectasia treatment is based on endoscopic ablation. More invasive options can be used if first-line therapies fail, although these should be evaluated on a case-by-case basis.
引用
收藏
页码:281 / +
页数:16
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