Lipidomics Insights in Health and Nutritional Intervention Studies

被引：32

作者：

Ibanez, Clara ^{[1
,2
]}

Mouhid, Lamia ^{[2
]}

Reglero, Guillermo ^{[1
,2
]}

Ramirez de Molina, Ana ^{[1
]}

机构：

[1] IMDEA Food Inst, Nutr Genom & Food GENYAL Platform, Crta Cantoblanco 8, Madrid 28049, Spain

[2] IMDEA Food Inst, Prod & Dev Foods Hlth, Crta Cantoblanco 8, Madrid 28049, Spain

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2017年 / 65卷 / 36期

关键词：

health; lipidomics; mass spectrometry; nuclear magnetic resonance; nutrition; POLYUNSATURATED FATTY-ACIDS; SPECTROMETRY-BASED METABOLOMICS; MASS-SPECTROMETRY; MEDITERRANEAN DIET; ADIPOSE-TISSUE; CARDIOVASCULAR-DISEASE; PLASMA LIPIDOMICS; FISH CONSUMPTION; BREAST-CANCER; NORDIC DIET;

D O I：

10.1021/acs.jafc.7b02643

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Lipids are among the major components of food and constitute the principal structural biomolecules of human body together with proteins and carbohydrates. Lipidomics encompasses the investigation of the lipidome, defined as the entire spectrum of lipids in a biological system at a given time. Among metabolomics technologies, lipidomics has evolved due to the relevance of lipids in nutrition and their well-recognized roles in health. Mass spectrometry advances have greatly facilitated lipidomics, but owing to the complexity and diversity of the lipids, lipidome purification and analysis are still challenging. This review focuses on lipidomics strategies, applications, and achievements of studies related to nutrition and health research.

引用

页码：7827 / 7842

页数：16

共 124 条

[1] The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism [J].

Acharjee, Animesh ;

Prentice, Philippa ;

Acerini, Carlo ;

Smith, James ;

Hughes, Ieuan A. ;

Ong, Ken ;

Griffin, Julian L. ;

Dunger, David ;

Koulman, Albert .

METABOLOMICS, 2017, 13 (03)

[2] Effects of a healthy Nordic diet on cardiovascular risk factors in hypercholesterolaemic subjects: a randomized controlled trial (NORDIET) [J].

Adamsson, V. ;

Reumark, A. ;

Fredriksson, I. -B. ;

Hammarstrom, E. ;

Vessby, B. ;

Johansson, G. ;

Riserus, U. .

JOURNAL OF INTERNAL MEDICINE, 2011, 269 (02) :150-159

[3] Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics [J].

Altmaier, Elisabeth ;

Kastenmueller, Gabi ;

Roemisch-Margl, Werner ;

Thorand, Barbara ;

Weinberger, Klaus M. ;

Adamski, Jerzy ;

Illig, Thomas ;

Doering, Angela ;

Suhre, Karsten .

MOLECULAR NUTRITION & FOOD RESEARCH, 2009, 53 (11) :1357-1365

[4]

Ander Bradley P, 2003, Exp Clin Cardiol, V8, P164

[5] Discovery and validation of urinary exposure markers for different plant foods by untargeted metabolomics [J].

Andersen, Maj-Britt Schmidt ;

Kristensen, Mette ;

Manach, Claudine ;

Pujos-Guillot, Estelle ;

Poulsen, Sanne Kellebjerg ;

Larsen, Thomas Meinert ;

Astrup, Arne ;

Dragsted, Lars .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2014, 406 (07) :1829-1844

[6] Obesity Epidemiology Worldwide [J].

Arroyo-Johnson, Cassandra ;

Mincey, Krista D. .

GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2016, 45 (04) :571-+

[7] A Protective Lipidomic Biosignature Associated with a Balanced Omega-6/Omega-3 Ratio in fat-1 Transgenic Mice [J].

Astarita, Giuseppe ;

McKenzie, Jennifer H. ;

Wang, Bin ;

Strassburg, Katrin ;

Doneanu, Angela ;

Johnson, Jay ;

Baker, Andrew ;

Hankemeier, Thomas ;

Murphy, James ;

Vreeken, Rob J. ;

Langridge, James ;

Kang, Jing X. .

PLOS ONE, 2014, 9 (04)

[8] Traceability in a food supply chain: Safety and quality perspectives [J].

Aung, Myo Min ;

Chang, Yoon Seok .

FOOD CONTROL, 2014, 39 :172-184

[9] Metabolomics Applied to Diabetes Research Moving From Information to Knowledge [J].

Bain, James R. ;

Stevens, Robert D. ;

Wenner, Brett R. ;

Ilkayeva, Olga ;

Muoio, Deborah M. ;

Newgard, Christopher B. .

DIABETES, 2009, 58 (11) :2429-2443

[10] Metabolomic approach to the nutraceutical effect of rosemary extract plus ω-3 PUFAs in diabetic children with capillary electrophoresis [J].

Balderas, Claudia ;

Villasenor, Alma ;

Garcia, Antonia ;

Ruperez, F. Javier ;

Ibanez, Elena ;

Senorans, Javier ;

Guerrero-Fernandez, Julio ;

Gonzalez-Casado, Isabel ;

Gracia-Bouthelier, Ricardo ;

Barbas, Coral .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2010, 53 (05) :1298-1304

← 1 2 3 4 5 6 7 8 9 10 →