Preparing (Multi)Fluoroarenes as Building Blocks for Synthesis: Nickel-Catalyzed Borylation of Polyfluoroarenes via C-F Bond Cleavage

被引：173

作者：

Zhou, Jing ^{[1
,2
]}

Kuntze-Fechner, Maximilian W. ^{[2
]}

Bertermann, Ruediger ^{[2
]}

Paul, Ursula S. D. ^{[2
]}

Berthel, Johannes H. J. ^{[2
]}

Friedrich, Alexandra ^{[2
]}

Du, Zhenting ^{[1
]}

Marder, Todd B. ^{[2
]}

Radius, Udo ^{[2
]}

机构：

[1] Northwest A&F Univ, Coll Sci, Yangling 712100, Shaanxi, Peoples R China

[2] Univ Wurzburg, Inst Anorgan Chem, Hubland, D-97074 Wurzburg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2016年 / 138卷 / 16期

关键词：

CROSS-COUPLING REACTIONS; ARYL HALIDES; ROOM-TEMPERATURE; ACTIVATION; FUNCTIONALIZATION; COMPLEXES; HYDRODEFLUORINATION; FLUOROPYRIDINES; SELECTIVITY;

D O I：

10.1021/jacs.6b02337

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The [Ni(IMes)(2)]-catalyzed transformation of fluoroarenes into arylboronic acid pinacol esters via C-F bond activation and transmetalation with bis(pinacolato)diboron (B(2)pin(2)) is reported. Various partially fluorinated arenes with different degrees of fluorination were converted into their corresponding boronate esters.

引用

页码：5250 / 5253

页数：4

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